Recombination induced by triple-helix-targeted DNA damage in mammalian cells
Explore this paper's citation graph
Summary
The ability to specifically induce recombination or gene conversion within mammalian cells by using TFOs may provide a new research tool and may eventually lead to novel applications in gene therapy.
- Type
- article
- Published
- 1996-12-01
- Cited by
- 99
- References
- 51
- Access
- Open access
- OpenAlex
- https://openalex.org/W1861710003
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:44487144
Keywords
Biology, Homologous recombination, Gene conversion, Gene targeting, Mutant
References
- Targeted mutagenesis of simian virus 40 DNA mediated by a triple helix-forming oligonucleotide
- In vitro repair of psoralen-DNA cross-links by RecA, UvrABC, and the 5'-exonuclease of DNA polymerase I.
- Use of psoralen-modified oligonucleotides to trap three-stranded RecA-DNA complexes and repair of these cross-linked complexes by ABC excinuclease.
- Analysis of sequential steps of nucleotide excision repair in Escherichia coli using synthetic substrates containing single psoralen adducts.
- Initiation of genetic exchanges in lambda phage--prophage crosses.
- Involvement of single-stranded tails in homologous recombination of DNA injected into Xenopus laevis oocyte nuclei.
- The role and fate of DNA ends for homologous recombination in embryonic stem cells
- Intermolecular recombination between DNAs introduced into mouse L cells is mediated by a nonconservative pathway that leads to crossover products
- Mismatch Repair of Heteroduplex DNA Intermediates of Extrachromosomal Recombination in Mammalian Cells
- Site-specific targeting of psoralen photoadducts with a triple helix-forming oligonucleotide: characterization of psoralen monoadduct and crosslink formation.
- Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes
- In vivo transcription of a progesterone-responsive gene is specifically inhibited by a triplex-forming oligonucleotide.
- Sequence-specific artificial photo-induced endonucleases based on triple helix-forming oligonucleotides
- Mutagenesis by third-strand-directed psoralen adducts in repair-deficient human cells: high frequency and altered spectrum in a xeroderma pigmentosum variant.
- High frequency targeting of genes to specific sites in the mammalian genome.
- Second structural motif for recognition of DNA by oligonucleotide-directed triple-helix formation.
- Specificity in formation of triple-stranded nucleic acid helical complexes: studies with agarose-linked polyribonucleotide affinity columns.
- Site-specific cleavage of human chromosome 4 mediated by triple-helix formation.
- Frequency of intrachromosomal homologous recombination induced by UV radiation in normally repairing and excision repair-deficient human cells.
- Incision by UvrABC excinuclease is a step in the path to mutagenesis by psoralen crosslinks in Escherichia coli.
Cited by
- Development and application of non-integrating lentiviral vectors for gene therapy
- Targeted Correction of an Episomal Gene in Mammalian Cells by a Short DNA Fragment Tethered to a Triplex-forming Oligonucleotide*
- Targeted gene correction using psoralen, chlorambucil and camptothecin conjugates of triplex forming peptide nucleic acid (PNA)
- Triplex forming oligonucleotides--tool for gene targeting.
- Using nucleases to stimulate homologous recombination.
- Unstable Coronary Artery Syndromes Pathophysiology, Diagnosis and Treatment
- Gene targeting via triple-helix formation.
- DNA repair and chromatin structure in genetic diseases.
- Origins of Programmable Nucleases for Genome Engineering
- Homology-directed Fanconi anemia pathway crosslink repair is dependent on DNA replication
- The use of zinc finger peptides to study the role of specific factor binding sites in the chromatin environment.
- Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells.
- Triplex‐Stabilizing Properties of Parallel Clamps Carrying LNA Derivatives at the Hoogsteen Strand
- Monitoring triplex DNA formation with fluorescence resonance energy transfer between a fluorophore-labeled probe and intercalating dyes.
- Oligo/Polynucleotide-Based Gene Modification: Strategies and Therapeutic Potential
- DNA INTERSTRAND CROSSLINK REPAIR IN MAMMALIAN CELLS: STEP BY STEP
- Mutation in Brca2 stimulates error‐prone homology‐directed repair of DNA double‐strand breaks occurring between repeated sequences
- High‐affinity triplex‐forming oligonucleotide target sequences in mammalian genomes
- Regulation of Gene Expression via Triple Helical Formations
- High-frequency intrachromosomal gene conversion induced by triplex-forming oligonucleotides microinjected into mouse cells.
Related papers
- Development of a Targeted Flip-in System in Avian DT40 Cells
- Use of gene targeting to study recombination in mammalian cell DNA repair mutants.
- Gene targeting is enhanced in human cells overexpressing hRAD51
- DNA oligonucleotide-assisted genetic manipulation increases transformation and homologous recombination efficiencies: Evidence from gene targeting of Dictyostelium discoideum.
- Use of gene targeting to study recombination in mammalian DNA repair mutants.
- Homologous gene targeting in Caenorhabditis elegans by biolistic transformation.
- Targeted gene conversion induced by triplex-directed psoralen interstrand crosslinks in mammalian cells
- Genetics of genetics in Drosophila: P elements serving the study of homologous recombination, gene conversion and targeting