Hypersensitivity to Hg2+ and hyperbinding activity associated with cloned fragments of the mercurial resistance operon of plasmid NR1
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Summary
The region of plasmid NR1 concerned with resistance to Hg2+ and organomercurials consists of sequences found on restriction endonuclease fragments Eco RI-H and EcoRI-I, which was associated with an inducible hyperbinding activity attributed to a gene governing Hg 2+ uptake and found on fragment EcoRI -H (which contains the proximal portion of a mercuric resistance [mer] operon).
- Type
- article
- Published
- 1979-10-01
- Cited by
- 94
- References
- 24
- Access
- Open access
- OpenAlex
- https://openalex.org/W1860649488
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:10698996
Keywords
EcoRI, Plasmid, ColE1, Molecular biology, Biology
References
- EcoRI restriction endonuclease map of the composite R plasmid NR1
- Deletions in the r-determinant mer region of plasmid R100-1 selected for loss of mercury hypersensitivy
- Mercury and Organomercurial Resistances Determined by Plasmids in Staphylococcus aureus
- Transposon A-generated mutations in the mercuric resistance genes of plasmid R100-1
- Properties of lambda transducing bacteriophages carrying R100 plasmid DNA: mercury resistance genes
- Induction by Mercuric Ion of Extensive Degradation of Cellular Ribonucleic Acid in Escherichia coli
- The folding and quaternary structure of trimeric 2-keto-3-deoxy-6-phosphogluconic aldolase at 3.5-A resolution.
- Mercurated polynucleotides: new probes for hybridization and selective polymer fractionation.
- Volatilisation of mercury and organomercurials determined by inducible R-factor systems in enteric bacteria
- Cell-Free Mercury(II)-Reducing Activity in a Plasmid-Bearing Strain of Escherichia coli
- Inhibition by Mercurial Reagents and Role of SH Groups of the Adenosine Triphosphatase from Escherichia coli 414 Membranes
- Microbial transformations of metals.
- Effect of Enzymatic Adenylylation on Dihydrostreptomycin Accumulation in Escherichia coli Carrying an R-Factor: Model Explaining Aminoglycoside Resistance by Inactivating Mechanisms
- Studies on the action of mercury
- Membranes and transport.
- Enzymes
- What Is the Mechanism of Plasmid-Determined Resistance to Aminoglycoside Antibiotics?
Cited by
- Plasmid-mediated heavy metal resistances.
- Genetically modified Escherichia coli for colorimetric detection of inorganic and organic Hg compounds.
- The structure of the mer operon.
- Cloning and DNA sequence analysis of the mercury resistance genes of Streptomyces lividans
- Tn5044-Conferred Mercury Resistance Depends on Temperature: the Complexity of the Character of Thermosensitivity
- Biological Mercury Reduction in the Environment and Its Policy Implications for Metals Regulations Based on Speciation
- Effect of catabolite repression on the mer operon
- Environmental Chemistry and Toxicology of Mercury: Liu/Toxicology of Mercury
- Simplified X-ray film method for detection of bacterial volatilization of mercury chloride by Escherichia coli
- Transcriptional analysis, translational analysis, and sequence of the kilA-tellurite resistance region of plasmid RK2Ter
- Nucleotide sequence of a chromosomal mercury resistance determinant from a Bacillus sp. with broad-spectrum mercury resistance
- Microbial transformations of mercury: potentials, challenges, and achievements in controlling mercury toxicity in the environment.
- Mercuric reductase enzyme from a mercury-volatilizing strain of Thiobacillus ferrooxidans
- Bacterial transformations of and resistances to heavy metals.
- Transposon A-generated mutations in the mercuric resistance genes of plasmid R100-1
- Pseudomonas putida Strains Which Constitutively Overexpress Mercury Resistance for Biodetoxification of Organomercurial Pollutants
- Mercury operon regulation by the merR gene of the organomercurial resistance system of plasmid pDU1358
- Cloning of plasmid genes encoding resistance to cadmium, zinc, and cobalt in Alcaligenes eutrophus CH34
- Biochemical characterization of HgCl2-inducible polypeptides encoded by the mer operon of plasmid R100
- Role of Na+ in transport of Hg2+ and induction of the Tn21 mer operon
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