Cross‐talk between pathogen recognizing Toll‐like receptors and immunoglobulin Fc receptors in immunity
Explore this paper's citation graph
Summary
The mechanisms of cross‐talk between different TLRs and FcRs and the resulting inflammatory immune responses are discussed and how chronic activation via this cross-talk might be detrimental in inflammatory (auto) immune diseases are proposed.
- Type
- review
- Published
- 2015-11-01
- Cited by
- 61
- References
- 110
- Access
- Open access
- OpenAlex
- https://openalex.org/W1859790752
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25951106
Keywords
Receptor, Immunology, Immune system, Biology, Opsonin
References
- Multitasking by Exploitation of Intracellular Transport Functions: The Many Faces of FcRn
- Fungal Recognition by TLR2 and Dectin-1.
- New insights on the signaling and function of the high-affinity receptor for IgE.
- Bridging autoantibodies and arthritis: the role of Fc receptors.
- Intracellular antibody immunity and the cytosolic Fc receptor TRIM21.
- FcγRs in health and disease.
- Activation of human basophils by combined toll‐like receptor‐ and FcεRI‐triggering can promote Th2 skewing of naive T helper cells
- Antibody-Opsonized Bacteria Evoke an Inflammatory Dendritic Cell Phenotype and Polyfunctional Th Cells by Cross-Talk between TLRs and FcRs
- Fc receptor-dependent mechanisms of monoclonal antibody therapy of cancer.
- Antibody‐mediated modulation of immune responses
- Toll-like receptors: Activation, signalling and transcriptional modulation.
- Trial Watch
- Intracellular antibody-bound pathogens stimulate immune signaling via Fc-receptor TRIM21
- Role of TREM-1 in response to Aspergillus fumigatus infection in corneal epithelial cells.
- How ITAMs Inhibit Signaling
- Dendritic cells and C‐type lectin receptors: coupling innate to adaptive immune responses
- A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene
- Innate signaling and regulation of Dendritic cell immunity.
- A role for the ITAM signaling module in specifying cytokine-receptor functions
- Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells.
Cited by
- FcγRIIIa-Syk Co-signal Modulates CD4+ T-cell Response and Up-regulates Toll-like Receptor (TLR) Expression*
- Polarization of M1 tumor associated macrophage promoted by the activation of TLR3 signal pathway.
- Avaliação fenotípica e funcional de células dendríticas inflamatórias na dermatite atópica do adulto
- Human CD4+ T-Cells: A Role for Low-Affinity Fc Receptors
- A novel role for β2-microglobulin: a precursor of antibacterial chemokine in respiratory epithelial cells
- Evidence of regulatory myeloid dendritic cells and circulating inflammatory epidermal dendritic cells‐like modulated by Toll‐like receptors 2 and 7/8 in adults with atopic dermatitis
- Fcγ Receptor Heterogeneity in Leukocyte Functional Responses
- Metabolic regulation of immunological synergism between Toll-like receptor and Fc-receptor signalling
- The Immunoregulatory Roles of Antibody Glycosylation.
- FcγRIIIa Signaling Modulates Endosomal Toll-Like Receptors Responses in Human CD4+ T-cells
- B Cell Extrinsic Myd88 and Fcer1g Negatively Regulate Autoreactive and Normal B cell Immune Responses
- FcγRIIb attenuates TLR4‑mediated NF‑κB signaling in B cells.
- Beyond binding: antibody effector functions in infectious diseases
- Immune complex negatively regulates toll-like receptor 3-triggered tumour necrosis factor α production in B cells
- Emerging Concepts in Immune Thrombocytopenia
- Toll-like receptors-mediated pathways activate inflammatory responses in the esophageal mucosa of adult eosinophilic esophagitis
- Murine macrophage TLR2-FcγR synergy via FcγR licensing of IL-6 cytokine mRNA ribosome binding and translation
- Fcγ Receptor Type I (CD64)-Mediated Impairment of the Capacity of Dendritic Cells to Activate Specific CD8 T Cells by IgG-opsonized Friend Virus
- Inside-Out Control of Fc-Receptors
- The Human FcγRII (CD32) Family of Leukocyte FcR in Health and Disease
Related papers
- Phagocytosis of immune complexes by human neutrophils and monocytes: relative importance of Fc and C3b receptors.
- Targeting pattern-recognition receptors to discover new small molecule immune modulators.
- Viral recognition by the innate immune system : the role of pattern recognition receptors *
- Viral recognition by the innate immune system: the role of pattern recognition receptors
- Intracellular PRRs Activation in Targeting the Immune Response Against Fungal Infections
- Role of the dual interaction of fungal pathogens with pattern recognition receptors in the activation and modulation of host defence.
- Structural aspects of molecular recognition in the immune system. Part II: Pattern recognition receptors (IUPAC Technical Report)
- Innate immune recognition.