Interaction between flavonoids and the blood–brain barrier: in vitro studies
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Summary
It is demonstrated that flavonoids and some metabolites are able to traverse the blood–brain barrier (BBB) and that the potential for permeation is consistent with compound lipophilicity.
- Type
- article
- Published
- 2003-04-01
- Cited by
- 589
- References
- 50
- OpenAlex
- https://openalex.org/W1824652155
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:22798171
Keywords
Hesperetin, Naringenin, Blood–brain barrier, Chemistry, In vivo
References
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- Oxidative stress, glutamate, and neurodegenerative disorders.
Cited by
- Naringenin, a flavanone inhibits the proliferation of cerebrally implanted C6 glioma cells in rats.
- Antioxidative and Chemopreventive Properties of Vernonia amygdalina and Garcinia biflavonoid
- Hesperidin Inhibits Inflammatory Response Induced by Aeromonas hydrophila Infection and Alters CD4+/CD8+ T Cell Ratio
- Hesperidin ameliorates behavioral impairments and neuropathology of transgenic APP/PS1 mice.
- Antagonistic Effects of Gingko biloba and Sophora japonica on Cerebral Vasoconstriction in Response to Histamine, 5-Hydroxytryptamine, U46619 and Bradykinin.
- Beneficial Effects of Hesperetin in a Mouse Model of Temporal Lobe Epilepsy
- Maternal prenatal consumption of bioflavonoids and phenolic acids and risk of childhood brain cancer
- Protection of apigenin against kainate-induced excitotoxicity by anti-oxidative effects.
- Polyphenols and Neurodegenerative Diseases
- Ingredients for Functional Drinks in Neurodegenerative Diseases: A Review
- Diseño de nuevas bebidas funcionales enriquecidas en fitoquímicos bioactivos = Design of new functional beverages rich in bioactive phytochemicals
- Metabolism and Anti-inflammatory Activity of Anthocyanins in Human Oral Cavity
- Anti-diabetic and neuroprotective activities of phytochemicals in traditionally used boreal plants
- Effects of Muscone on the Expression of P-gp, MMP-9 on Blood–Brain Barrier Model In Vitro
- Effect of perinatally supplemented flavonoids on brain structure, circulation, cognition, and metabolism in C57BL/6J mice.
- Étude des propriétés biologiques des constituants des vins de Champagne
- EFFECTS OF RED RASPBERRY ON DOXORUBICIN CHEMOTHERAPY INDUCED NEUROTOXICITY
- Bioavailability of dietary polyphenols: Factors contributing to their clinical application in CNS diseases.
- Pharmacokinetic Profiles of Active Ingredients and Its Metabolites Derived from Rikkunshito, a Ghrelin Enhancer, in Healthy Japanese Volunteers: A Cross-Over, Randomized Study
- Nano-antioxidants: An emerging strategy for intervention against neurodegenerative conditions.
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