Enteral glutamine supplementation in critically ill patients: a systematic review and meta-analysis
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Summary
Enteral GLN supplementation does not confer significant clinical benefit in critically ill patients, with the exception of reduced hospital stay, and larger randomized trials are warranted to confirm this effect.
- Type
- review
- Published
- 2015-08-18
- Cited by
- 109
- References
- 89
- Access
- Open access
- OpenAlex
- https://openalex.org/W1822346164
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:15966220
Keywords
Medicine, Enteral administration, Parenteral nutrition, Glutamine, Internal medicine
References
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- Glutamine attenuates post-traumatic glutathione depletion in human muscle.
- The feeding route (enteral or parenteral) affects the plasma response of the dipetide Ala-Gln and the amino acids glutamine, citrulline and arginine, with the administration of Ala-Gln in preoperative patients
- Endogenous glutamine production in critically ill patients: the effect of exogenous glutamine supplementation
- Effect of long-term oral glutamine supplements on small intestinal permeability in patients with Crohn's disease.
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- Effect of glutamine in short-bowel syndrome.
- Synbiotics, prebiotics, glutamine, or peptide in early enteral nutrition: a randomized study in trauma patients.
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- A pilot study of oral glutamine supplementation in patients receiving bone marrow transplants.
- Total parenteral nutrition in the critically ill patient: a meta-analysis.
Cited by
- Association of intestinal permeability with a NUTRIC score in critically ill patients.
- Nutritional controversies in critical care: revisiting enteral glutamine during critical illness and injury
- Plasma glutamine concentration after intensive care unit discharge: an observational study
- Glutamine May Repress the Weak LPS and Enhance the Strong Heat Shock Induction of Monocyte and Lymphocyte HSP72 Proteins but May Not Modulate the HSP72 mRNA in Patients with Sepsis or Trauma
- Enteral glutamine supplementation in critically ill patients
- Exogenous Glutamine in Respiratory Diseases: Myth or Reality?
- Immunonutrition for acute respiratory distress syndrome (ARDS) in adults.
- Should We Increase Protein Delivery During Critical Illness?
- Enteral versus parenteral nutrition in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials
- Immune-Enhancing Diets: What is the Final Answer?
- Impact of decreasing energy intakes in major burn patients: A 15-year retrospective cohort study.
- When Is It Appropriate to Use Glutamine in Critical Illness?
- Nutrition in burn injury: any recent changes?
- Glutamine in critically ill patients: is it a fundamental nutritional supplement?
- Immunonutrition and Amino Acids
- Librarian Involvement in Systematic Reviews at Queen’s University: An Environmental Scan
- Poor methodological quality and reporting standards of systematic reviews in burn care management
- Nutrition in the critically ill patient
- The intensive care medicine research agenda in nutrition and metabolism
- Therapeutic Benefits of Glutamine: An Umbrella Review of Meta‐Analyses
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