High-resolution analysis of DNA replication domain organization across an R/G-band boundary
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Summary
This study analyzes the replication timing of markers spanning roughly 5 Mb of human chromosome 13q14.3/q21.1 to determine a boundary between differentially replicating chromosomal bands, finding that band boundaries are defined by a gradient in replication timing rather than by a sharp boundary separating R and G bands into functionally distinct chromatin compartments.
- Type
- article
- Published
- 1997-10-01
- Cited by
- 43
- References
- 59
- Access
- Open access
- OpenAlex
- https://openalex.org/W1821233703
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:23136936
Keywords
Replication timing, Biology, Chromatin, Chromosome, Origin of replication
References
- Minimal region of loss at 13q14 in B-cell chronic lymphocytic leukemia.
- Detection of DNA sequence polymorphisms by enzymatic amplification and direct genomic sequencing.
- Origins of DNA replication in metazoan chromosomes.
- Technical aspects of quantitative competitive PCR.
- Activation and repression of a beta-globin gene in cell hybrids is accompanied by a shift in its temporal replication
- Delineation of DNA replication time zones by fluorescence in situ hybridization.
- Chromosome bands, their chromatin flavors, and their functional features.
- Regulation of DNA replication on subchromosomal units of mammalian cells
- Asynchronous DNA replication within the human beta-globin gene locus.
- Structure and organization of GABRB3 and GABRA5.
- In situ localization of mitochondrial DNA replication in intact mammalian cells
- Evidence that both G + C rich and G + C poor isochores are replicated early and late in the cell cycle.
- Isolation of human chromosome 13-specific DNA sequences cloned from flow sorted chromosomes and potentially linked to the retinoblastoma locus.
- The gene distribution of the human genome.
- A novel procedure for quantitative polymerase chain reaction by coamplification of competitive templates.
- Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector.
- Metaphase chromosome structure: bands arise from a differential folding path of the highly AT-rich scaffold.
- A boundary of long-range G + C% mosaic domains in the human MHC locus: pseudoautosomal boundary-like sequence exists near the boundary.
- Complementary replication R- and G-band patterns induced by cell blocking at the R-band/G-band transition, a possible regulatory checkpoint within the S phase of the cell cycle.
- Searching for replication origins in mammalian DNA.
Cited by
- Introduction to molecular combing: genomics, DNA replication, and cancer.
- Initiation of DNA Replication in Cells of Higher Eukaryotes
- Developing models of the mammalian cell S phase
- DNA replication in the human major histocompatibility complex.
- Genomic domains and regulatory elements operating at the domain level.
- Kinetics of DNA replication and telomerase reaction at a single‐seeded telomere in human cells
- Mapping of an origin of DNA replication near the transcriptional promoter of the human HPRT gene
- Replication timing properties across the pseudoautosomal region boundary and cytogenetic band boundaries on human distal Xp
- Regulation of DNA replication timing
- An isochore transition zone in the NF1 gene region is a conserved landmark of chromosome structure and function.
- Profiling of DNA replication timing in unsynchronized cell populations
- Evolutionary genomics: reading the bands.
- Regulation of DNA Replication Timing on Human Chromosome by a Cell-Type Specific DNA Binding Protein SATB1
- Evidence that a single replication fork proceeds from early to late replicating domains in the IgH locus in a non-B cell line.
- Transitions in replication timing in a 340 kb region of human chromosomal R‐Band 1p36.1
- Characterization of two novel protocadherins (PCDH8 and PCDH9) localized on human chromosome 13 and mouse chromosome 14.
- Isochores and replication time zones: a perfect match
- Regulation of replication at the R/G chromosomal band boundary and pericentromeric heterochromatin of mammalian cells.
- Replication timing of the human X-inactivation center (XIC) region: correlation with chromosome bands.
- S-phase progression in mammalian cells: modelling the influence of nuclear organization
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