Vascular integrin alpha(v)beta3: a new prognostic indicator in breast cancer.
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Summary
The findings support the contention that angiogenesis plays a critical role in breast cancer progression and suggest that integrin alpha(v)beta3 is an endothelial cell marker with significant prognostic value and potential usefulness as a target for specific antiangiogenic therapy.
- Type
- article
- Published
- 1998-11-01
- Cited by
- 290
- References
- 24
- OpenAlex
- https://openalex.org/W1817837574
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:36058486
Keywords
Breast cancer, CD31, Angiogenesis, Metastasis, Medicine
References
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Cited by
- Breast cancer biomarkers.
- Role of the Tumor Microenvironment in Mediating Response to Anti-angiogenic Therapy
- Enhancing Surgical Vision by Using Real-Time Imaging of αvβ3-Integrin Targeted Near-Infrared Fluorescent Agent
- Novel peptide targeting integrin αvβ3‐rich tumor cells by magnetic resonance imaging
- Assessing tumor angiogenesis in histological samples.
- Mechanisms mediated by CXCL12 signaling through CXCR4 and CXCR7 in breast cancer.
- Tumor endothelial cells are targets for selective therapies: in vitro and in vivo models to evaluate antiangiogenic strategies.
- Toward Checkmate: Biology and Breast Cancer Therapy for the New Millennium
- Positron emission tomography (PET): Expanding the horizons of oncology drug development
- Angiogenesis and Cancer Control: From Concept to Therapeutic Trial.
- Defining The Mechanism Of Enhanced Cellular Invasion Induced By Mechanical Stimulation
- MASTOCITOMA CANINO: ABORDAGEM HISTOPATOLÓGICA E IMUNOISTOQUÍMICA NA BUSCA DE BIOMARCADORES PROGNÓSTICOS
- Parathyroid hormone-related peptide : a key factor in cell adhesion.
- Fibrinogen synthesized by cancer cells augments the proliferative effect of fibroblast growth factor‐2 (FGF‐2)
- Increased invasive potential and up-regulation of MMP-2 in MDA-MB-231 breast cancer cells expressing the beta3 integrin subunit.
- Integrin αvβ3 Expression in Colon Carcinoma Correlates with Survival
- Anti-angiogenic therapy: Rationale, challenges and clinical studies
- Endothelial Cells of Tumor Vessels: Abnormal but not Absent
- IGF:VN complexes and their role in breast cell migration
- EVALUATION DE NOUVEAUX RADIOPHARMACEUTIQUES Synthèse, évaluation, et biodistribution de nouveaux radioligands peptidiques de VCAM-1 et avb3
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