L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L.
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Summary
It was shown that the rapid stoichiometric reaction of the cysteine proteinases related to papain can be used to determine the operational molarity of solutions of the enzymes and thus to calibrate rate assays.
- Type
- article
- Published
- 1982-01-01
- Cited by
- 951
- References
- 0
- Access
- Open access
- OpenAlex
- https://openalex.org/W1812339273
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24391435
Keywords
Thermolysin, Leupeptin, Chemistry, Cathepsin B, Cathepsin C
References
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