Rapid assay for evaluating the chemosensitivity of human tumors in soft agar culture.
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Summary
This scintillation assay accurately predicted drug-tumor interactions within 5 days that resulted in a 75% or greater decrease in colonies.
- Type
- article
- Published
- 1982-06-01
- Cited by
- 146
- References
- 28
- OpenAlex
- https://openalex.org/W1792509681
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:14330555
Keywords
Chemosensitivity assay, Cell counting, Adenocarcinoma, Population, Pathology
References
- In vitro effects on DNA synthesis as a predictor of biological effect from chemotherapy.
- Preparation of permanent slides of intact soft-agar colony cultures of hematopoietic and tumor stem cells.
- Primary bioassay of human myeloma stem cells.
- In vitro estimate of sensitivity of individual human tumors to antitumor agents.
- Prediction of therapeutic response in acute leukaemia.
- Association between human tumor colony-forming assay results and response of an individual patient's tumor to chemotherapy.
- Tissue-culture microtest for predicting response of human cancer to chemotherapy.
- Liquid scintillation technique for the determination of DNA synthesis of lymphocytes cultured in plastic vessels.
- Serial labeling index determination as a predictor of response in human solid tumors.
- Inhibition of human ovarian cancer colony formation by adriamycin and its major metabolites.
- Direct cloning of human ovarian carcinoma cells in agar.
- Characterization of cells obtained by mechanical and enzymatic means from human melanoma, sarcoma, and lung tumors.
- Kinetic alterations induced by 5-fluorouracil in bone marrow, intestinal mucosa, and tumor.
- Colony growth in agar by human melanoma cells.
- Growth of cell colonies in soft agar from biopsies of different human solid tumors.
- Rapid assays for evaluating the drug sensitivity of tumor cells.
- Cell kinetic analysis of human tumor stem cells.
- Primary bioassay of human tumor stem cells.
Cited by
- Soft agarose culture human tumour colony forming assay for drug sensitivity testing: [3H]-thymidine incorporation vs colony counting.
- Cell patterning by micro-pattern projection of UV light through photoinduced enhancement of cell adhesion (PIECA).
- A simple colorimetric method for the evaluation of growth and chemosensitivity of tumor cells in soft agar culture.
- Cytotoxicity testing in vitro: investigation of 5 miniaturized, colorimetric assays
- Development of a new in vitro chemosensitivity test using collagen gel droplet embedded culture and image analysis for clinical usefulness.
- Effects of interleukin-4 on the in vitro growth of human lymphoid and plasma cell neoplasms.
- Soft agarose colony formation assay for human renal cell carcinoma: comparison of optical colony counting versus tritiated thymidine incorporation.
- Balb/3T3細胞のcontact-sensitivemonolayer(cell mat)を利用したヒト癌細胞の抗癌剤感受性試験
- Clinical studies on a new screening assay for anticancer agents using nude mice and isotopic evaluation.
- Growth inhibition of human tumor cells in soft-agar cultures by treatment with low levels of adenosine 5'-triphosphate.
- Rapid assay for thein vitro chemosensitivity testing of human breast tumours
- Exploratory phase II trial in a multicenter setting to evaluate the clinical value of a chemosensitivity test in patients with gastric cancer (JACCRO-GC 04, Kubota memorial trial)
- Improvement of in vitro chemosensitivity assay for human solid tumors by application of a preculture using collagen matrix.
- Colony-forming ability in vitro and clonology of colorectal cancer.
- Establishment and characterization of two new cell lines derived from human metastatic breast carcinomas
- Vasoactive intestinal peptide inhibits human small-cell lung cancer proliferation in vitro and in vivo.
- In vitro chemotherapy sensitivity testing of human ovarian carcinoma: comparison of optical colony counting and [3H]thymidine incorporation assays.
- Chemosensitivity testing: another chapter.
- Adenovirus replication as an in vitro probe for drug sensitivity in human tumors.
- Chromosomal alterations, biological features and in vitro chemosensitivity of SCLC-R1, a new cell line from human metastatic small cell lung carcinoma.
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