Kalirin Dbl-Homology Guanine Nucleotide Exchange Factor 1 Domain Initiates New Axon Outgrowths via RhoG-Mediated Mechanisms

Keywords

Guanine nucleotide exchange factor, RHOA, Cell biology, Biology, RAC1

References

• RHO GTPASES in neuronal morphogenesisLiqun Luo — 2000
• Distinct Roles for the Two Rho GDP/GTP Exchange Factor Domains of Kalirin in Regulation of Neurite Growth and Neuronal MorphologyPeter Penzes, Richard C. Johnson, Vikram Kambampati — 2001
• The Rac1- and RhoG-specific GEF domain of Trio targets filamin to remodel cytoskeletal actinJean‐Michel Bellanger, Catherine Astier, Claude Sardet — 2000
• The Transmembrane Protein Semaphorin 6A Repels Embryonic Sympathetic AxonsXiaomei Xu, Daniel A.C. Fisher, Lijuan Zhou — 2000
• The establishment of polarity by hippocampal neurons in cultureCarlos G. Dotti, CA Sullivan, GA Banker — 1988
• Drosophila Rac1 controls motor axon guidance.Nancy Kaufmann, Zachary P. Wills, David Van Vactor — 1998
• Differential regulation of sympathetic neuron neuropeptide Y and catecholamine content and secretionVíctor May, C A Brandenburg, KM Braas — 1995
• TrioGEF1 controls Rac- and Cdc42-dependent cell structures through the direct activation of rhoG.Anne Blangy, Emmanuel Vignal, Susanne Schmidt — 2000
• EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin.Steven M. Shamah, Michael Z. Lin, Jeffrey L. Goldberg — 2001
• Receptor and nonreceptor protein tyrosine phosphatases in the nervous systemSouradip Paul, PJ Lombroso — 2003
• Phosphorylation‐dependent and constitutive activation of Rho proteins by wild‐type and oncogenic Vav‐2Kornel E. Schuebel, Nieves Movilla, José Luis Rosa — 1998
• The Drosophila trio plays an essential role in patterning of axons by regulating their directional extension.Takeshi Awasaki, Mai Saito, Masaki Sone — 2000
• An emerging link between cytoskeletal dynamics and cell adhesion molecules in growth cone guidance.Daniel M. Suter, Paul Forscher — 1998
• The role of local actin instability in axon formation.Frank Bradke, Carlos G. Dotti — 1999
• Novel Proteins That Interact with the COOH-terminal Cytosolic Routing Determinants of an Integral Membrane Peptide-processing Enzyme*M. Rashidul Alam, Benjamin D. Caldwell, Richard C. Johnson — 1996
• Trio combines with dock to regulate Pak activity during photoreceptor axon pathfinding in Drosophila.Timothy P. Newsome, Susanne Schmidt, Georg Dietzl — 2000
• The transmembrane tyrosine phosphatase DLAR controls motor axon guidance in Drosophila.N. Krueger, David Van Vactor, Hong Wan — 1996
• Isoforms of Kalirin, a Neuronal Dbl Family Member, Generated through Use of Different 5′- and 3′-Ends Along with an Internal Translational Initiation Site*Richard C. Johnson, Peter Penzes, Betty Eipper — 2000
• Neuropilin-2 is a receptor for semaphorin IV: insight into the structural basis of receptor function and specificity.Roman J. Giger, Erica Rowe Urquhart, Susan Gillespie — 1998
• Expression of Kalirin, a neuronal GDP/GTP exchange factor of the Trio family, in the central nervous system of the adult ratXin‐Ming Ma, Richard C. Johnson, Richard E. Mains — 2001

Cited by

• Kalirin is Under-Expressed in Alzheimer's Disease HippocampusHyeSook Youn, Myoungkun Jeoung, Yongbum Koo — 2007
• The role of kalirin-7 in the pathogenesis of Parkinson disease and Huntington diseaseYu-Chun Tsai — 2012
• Function and Regulation of the Postsynaptic Exchange Factor, Kalirin-7Megan B. Miller — 2015
• Novel links between protein sorting and cytoskeletal dynamics in the secretory pathwayDerek C. Prosser — 2008
• Carboxypeptidase E is required for normal synaptic transmission from photoreceptors to the inner retinaXuemei Zhu, Kebin Wu, Lawrence Rife — 2005
• miR‐124‐regulated RhoG reduces neuronal process complexity via ELMO/Dock180/Rac1 and Cdc42 signallingKristin Franke, Wolfgang Otto, Sascha Johannes — 2012
• Isolation and characterization of neuronal substrates of the ubiquitin proteasome systemJ. M. Keil — 2011
• Structural Basis for the Signaling Specificity of RhoG and Rac1 GTPases*Rosario M. Prieto‐Sánchez, Xosé R. Bustelo — 2003
• Differential activation and function of Rho GTPases during Salmonella–host cell interactionsJayesh C. Patel, Jorge E. Galán — 2006
• Ephexin4 and EphA2 mediate resistance to anoikis through RhoG and phosphatidylinositol 3-kinase.Kohei Harada, Nao Hiramoto‐Yamaki, Masahiko Negishi — 2011
• Differential distribution of ELMO1 and ELMO2 mRNAs in the developing mouse brain.Hironori Katoh, Satoshi Fujimoto, Chisaki Ishida — 2006
• Crystal structure of human cytochrome P450 2C9 with bound warfarinPamela A. Williams, José Cosme, Alison Ward — 2003
• Involvement of the Rho/Rac family member RhoG in caveolar endocytosisRosario M. Prieto‐Sánchez, Inmaculada M. Berenjeno, Xosé R. Bustelo — 2006
• The nuclear factor kappaB-activator gene PLEKHG5 is mutated in a form of autosomal recessive lower motor neuron disease with childhood onset.Isabelle Maystadt, René Rezsöhazy, Martine Barkats — 2007
• Regulation of Kalirin by Cdk5Xiaonan Xin, Yanping Wang, Xin‐Ming Ma — 2008
• A Novel, Retromer‐Independent Role for Sorting Nexins 1 and 2 in RhoG‐Dependent Membrane RemodelingDerek C. Prosser, Duvinh Tran, Allana Schooley — 2010
• Involvement of Rho-family GTPases in axon branchingMirela Spillane, Gianluca Gallo — 2014
• RhoG activates Rac1 by direct interaction with the Dock180-binding protein ElmoHironori Katoh, Masahiko Negishi — 2003
• Activation of Rac1 by RhoG regulates cell migrationHironori Katoh, Kiyo Hiramoto, Masahiko Negishi — 2006
• The Novel GTPase Rit Differentially Regulates Axonal and Dendritic GrowthPamela J. Lein, Xin Guo, Geng‐Xian Shi — 2007

Related papers

• The yeast exchange assay, a new complementary method to screen for Dbl‐like protein specificity: identification of a novel RhoA exchange factorMarion de Toledo, Kelly Colombo, Takahiro Nagase — 2000
• SmgGDS Is a Guanine Nucleotide Exchange Factor That Specifically Activates RhoA and RhoC*Brant Hamel, Elizabeth Monaghan-Benson, Rafael J. Rojas — 2011
• RhoGEF Specificity Mutants Implicate RhoA as a Target for Dbs Transforming ActivityLi Cheng, Kent L. Rossman, Gwendolyn M. Mahon — 2002
• RhoA/ROCK-mediated switching between Cdc42- and Rac1-dependent protrusion in MTLn3 carcinoma cells.Mirvat El‐Sibai, Olivier Pertz, Huan Pang — 2008
• A Potent and Selective Inhibitor of Cdc42 GTPaseZurab Surviladze, Anna Waller, J. Jacob Strouse — 2010
• Abstract 3847: Cytoplasmic ECT2: Implications for invasion and migration and RAS-RAC cross-talk in gliomaAdrienne Weeks, Nadia Okolowsky, Stacey Ivanchuk — 2011
• Specific Recognition of Rac2 and Cdc42 by DOCK2 and DOCK9 Guanine Nucleotide Exchange Factors*Michael Kwofie, Jacek Skowroński — 2008
• RhoA and Rac1 signals in fMLP-induced NF-kappaB activation in human blood monocytes.Lingyu Chen, Andrzej Ptasznik, Zhixing K. Pan — 2004