Vascular toxicity associated with antineoplastic agents.

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Summary

Vascular complications associated with antineoplastic agents are being reported with increasing frequency and putative mechanisms for such toxicity include drug-induced endovascular damage, perturbation of the clotting system, platelet activation, an abnormality of thromboxane-prostacyclin homeostasis, autonomic dysfunction, vasculitis, and stimulation of fibroblasts.

Type
review
Published
1986-09-01
Cited by
282
References
175

Keywords

Medicine, Toxicity, Pharmacology, Internal medicine, Pathology

References

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