IFN-Stimulated Gene 15 Is Synergistically Activated Through Interactions Between the Myelocyte/Lymphocyte-Specific Transcription Factors, PU.1, IFN Regulatory Factor-8/IFN Consensus Sequence Binding Protein, and IFN Regulatory Factor-4: Characterization of a New Subtype of IFN-Stimulated Response El
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Summary
The results lay the molecular basis for the unique regulation of ISGs, harboring EIRE, in immune cells, which are differentially regulated inimmune cells.
- Type
- article
- Published
- 2002-06-15
- Cited by
- 120
- References
- 39
- Access
- Open access
- OpenAlex
- https://openalex.org/W1786654010
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:41027088
Keywords
Transcription factor, Interferon regulatory factors, Biology, IRF1, Response element
References
- Role of the double-stranded RNA-activated protein kinase (PKR) in cell regulation.
- Interaction between Interferon Consensus Sequence-binding Protein and COP9/Signalosome Subunit CSN2 (Trip15)
- SHP1 protein-tyrosine phosphatase inhibits gp91PHOX and p67PHOX expression by inhibiting interaction of PU.1, IRF1, interferon consensus sequence-binding protein, and CREB-binding protein with homologous Cis elements in the CYBB and NCF2 genes.
- Human interferon consensus sequence binding protein is a negative regulator of enhancer elements common to interferon-inducible genes.
- A two-step mechanism for recruitment of Pip by PU.1.
- Negative Regulation of CD8+ T Cell Function by the IFN-Induced and Double-Stranded RNA-Activated Kinase PKR1
- The Murine Chemokine CXCL11 (IFN-Inducible T Cell α Chemoattractant) Is an IFN-γ- and Lipopolysaccharide- Inducible Glucocorticoid-Attenuated Response Gene Expressed in Lung and Other Tissues During Endotoxemia1
- Functional domains of interferon regulatory factor I (IRF-1).
- High-efficiency transformation of mammalian cells by plasmid DNA.
- Phosphorylation Events Modulate the Ability of Interferon Consensus Sequence Binding Protein to Interact with Interferon Regulatory Factors and to Bind DNA*
- Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element.
- Transcription factor-specific requirements for coactivators and their acetyltransferase functions.
- The key role of PU.1/SPI-1 in B cells, myeloid cells and macrophages.
- Gene induction pathways mediated by distinct IRFs during viral infection.
- Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei.
- Precursor Processing of Pro-ISG15/UCRP, an Interferon-β-induced Ubiquitin-like Protein*
- An overview of the interferon system: signal transduction and mechanisms of action.
- Requirement for the Transcription Factor LSIRF/IRF4 for Mature B and T Lymphocyte Function
- Accumulation of an mRNA and protein in interferon-treated Ehrlich ascites tumour cells
- Functional Domain Analysis of Interferon Consensus Sequence Binding Protein (ICSBP) and Its Association with Interferon Regulatory Factors (*)
Cited by
- ISG15: a ubiquitin-like enigma.
- Toll-like receptor signaling and regulation of cytokine gene expression in the immune system.
- Role of IRF4 in the Regulation of Cellular Interferon Stimulated Genes and KSHV Lytic Gene Expression in Primary Effusion Lymphoma
- The innate antiviral response: new insights into a continuing story.
- Control of hepatitis C virus genome replication by viral factors and mediators of host intrinsic immunity
- The diverse roles of IRF4 in late germinal center B‐cell differentiation
- IFN-α-Induced Signal Transduction, Gene Expression, and Antitumor Activity of Immune Effector Cells Are Negatively Regulated by Suppressor of Cytokine Signaling Proteins1
- Cytokine-Induced Hepatic Apoptosis Is Dependent on FGL2/Fibroleukin: The Role of Sp1/Sp3 and STAT1/PU.1 Composite cis Elements
- IFNs, ISGylation and cancer: Cui prodest?
- Sequence and expression analysis of an interferon stimulated gene (ISG15) from Atlantic cod (Gadus morhua L.).
- Interferon Regulatory Factor 8 Regulates RANTES Gene Transcription in Cooperation with Interferon Regulatory Factor-1, NF-κB, and PU.1*
- Dynamic epigenetic enhancer signatures reveal key transcription factors associated with monocytic differentiation states.
- Regulation of immunity and oncogenesis by the IRF transcription factor family
- Building promoter aware transcriptional regulatory networks using siRNA perturbation and deepCAGE
- Functional characterization of the human dendritic cell immunodeficiency associated with the IRF8(K108E) mutation.
- Stimulation of Osteoclast Formation by RANKL Requires Interferon Regulatory Factor-4 and Is Inhibited by Simvastatin in a Mouse Model of Bone Loss
- The Small Interferon-Induced Transmembrane Genes and Proteins
- EBNA1 regulates cellular gene expression by binding cellular promoters
- The IRF family, revisited.
- Protein Tyrosine Phosphatase 1B in Hematopoiesis
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