Inhibition of lipopolysaccharide-initiated activation of serum complement by polymyxin B
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Summary
Treatment of bacterial lipopolysaccharides isolated from Salmonella minnesota R595 or purified lipid A with the antibiotic polymyxin B has been demonstrated to abrogate the ability of these molecules to activate serum complement.
- Type
- article
- Published
- 1976-01-01
- Cited by
- 77
- References
- 15
- Access
- Open access
- OpenAlex
- https://openalex.org/W1785910489
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:44081327
Keywords
Lipopolysaccharide, Polymyxin B, Lipid A, Polymyxin, Microbiology
References
- REDUCTION OF SERUM COMPLEMENT IN RABBITS AFTER INJECTION OF ENDOTOXIN
- Neutralization of the hemodynamic effects of endotoxin by polymyxin B.
- Prevention by polymyxin B of endotoxin lethality in mice
- Depletion of plasma complement in vivo by a protein of cobra venom: its effect on various immunologic reactions.
- The effects of antibiotics on enterobacterial lipopolysaccharides (endotoxins), hemagglutination and hemolysis.
- Interactions of the complement system with endotoxins from a Salmonella minnesota mutant deficient in O-polysaccharide and heptose.
- Chemistry and reaction mechanisms of complement.
- The Role of Complement in Endotoxin Shock and Disseminated Intravascular Coagulation: Experimental Observations in the Dog
- The behaviour of complement and platelets in lethal endotoxin shock in rabbits.
- Interaction of lipopolysaccharides and lipid A with complement.
- Neutralization of Endotoxin Toxicity in Chick Embryos by Antibiotics
- Dissociation between mitogenicity and immunogenicity of TNP- lipopolysaccharide, a T-independent antigen
- Interaction of complex polysaccharides with the complement system: effect of calcium depletion on terminal component consumption
Cited by
- Characterization of complex formation between lipopolysaccharide and lysozyme.
- Gonococcal lipopolysaccharide: a toxin for human fallopian tube mucosa.
- Complex Interactions Between Osteosarcoma Cells and Fibroblasts
- ESTUDO IN VIVO DA AÇÃO DO TRATAMENTO ENDODÔNTICO SOBRE ENDOTOXINAS BACTERIANAS EM CANAIS RADICULARES COM POLPA NECROSADA E AVALIAÇÃO DOS EFEITOS CITOTÓXICOS DO CONTEÚDO DO CANAL RADICULAR
- The effects of bacterial endotoxins on host mediation systems. A review.
- Biological activities residing in the Fc region of immunoglobulin.
- Constitutive production of interleukin 1 by human monocytic leukemia cell line JOSK-I and the production mechanism.
- Candida albicans‐induced inflammatory response in human keratinocytes
- Binding of lysozyme to lipopolysaccharide suppresses tumor necrosis factor production in vivo
- Polymyxins as inhibitors of polyclonal B-cell activators in murine lymphocyte cultures
- Polymyxin B Inactivation of Lipopolysaccharide in Vaccines of Gram-Negative Bacteria
- Influence of serum-derived chemotactic factors and bacterial products on human neutrophil chemotaxis
- Avaliação in vitro da ação de substâncias químicas auxiliares e medicações intracanais sobre Escherichia coli e sua endotoxina em canais radiculares
- Human complement activation by lipopolysaccharides from bacteroides oralis, fusobacterium nucleatum, and veillonella parvula
- Lipid A as the biologically active moiety in bacterial endotoxin (LPS)-initiated generation of procoagulant activity by peripheral blood leukocytes.
- Increased synthesis of fibrinolytic inhibitor induced by muramyl dipeptide derivatives in human cultured endothelial cells.
- Granulocyte-macrophage colony-stimulating factor binding sites and oxidative metabolism in human granulocytes
- Eggshell membrane hydrolyzates activate NF-κB in vitro: possible implications for in vivo efficacy
- Inactivation by polymyxin B of the endotoxin-mediated interferon production in the rabbit.
- The Secreted Products of Porphyromonas gingivalis Alter Human Gingival Fibroblast Morphology by Selective Damage to Integrin-Substrate Interactions
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