High-frequency disruption of the N-myc gene in embryonic stem and pre-B cell lines by homologous recombination

Keywords

Biology, Homologous recombination, Gene targeting, Gene, Embryonic stem cell

References

• Insertion of DNA sequences into the human chromosomal β-globin locus by homologous recombinationJinyan Huang, Kathleen J. Brown — 1985
• Definition of regions in human c-myc that are involved in transformation and nuclear localizationIva Thomas — 1987
• IgH enhancer‐mediated deregulation of N‐myc gene expression in transgenic mice: generation of lymphoid neoplasias that lack c‐myc expression.Renate Dildrop, Averil Ma, Kathryn A. Zimmerman — 1989
• Human proto-oncogene N-myc encodes nuclear proteins that bind DNAGary Ramsay, Lawrence W. Stanton, M. Schwab — 1986
• Identification and characterization of the protein encoded by the human N-myc oncogene.Dennis J. Slamon, Thomas C. Boone, Robert C. Seeger — 1986
• Contrasting patterns of myc and N-myc expression during gastrulation of the mouse embryo.Karen M. Downs, Gail R. Martin, J. Michael Bishop — 1989
• Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genesSuzanne L. Mansour, Kirk R. Thomas, Mario R. Capecchi — 1988
• Positive genetic selection for gene disruption in mammalian cells by homologous recombination.John M. Sedivy, Phillip A. Sharp — 1989
• Structure and expression of the murine N-myc gene.Ronald A. DePinho, Edith Legouy, Lori B. Feldman — 1986
• The human myc gene family: structure and activity of L-myc and an L-myc pseudogene.Ronald A. DePinho, K S Hatton, Abeba Tesfaye — 1987
• Expression of N-myc in teratocarcinoma stem cells and mouse embryosAya Jakobovits, Manfred Schwab, J. Michael Bishop — 1985
• Production of chimaeric mice containing embryonic stem (ES) cells carrying a homoeobox Hox 1.1 allele mutated by homologous recombinationAndreas Zimmer, Peter Gruss — 1989
• Production of a mutation in mouse En-2 gene by homologous recombination in embryonic stem cellsAlexandra L. Joyner, William C. Skarnes, Janet Rossant — 1989
• Towards a molecular-genetic analysis of mammalian development.Janet Rossant, Alexandra L. Joyner — 1989
• Differential expression of myc family genes during murine developmentKathryn A. Zimmerman, George D. Yancopoulos, Robert G. Collum — 1986
• N-myc can cooperate with ras to transform normal cells in culture.G D Yancopoulos, Perry D. Nisen, Abeba Tesfaye — 1985
• Proteins encoded by v-myc and c-myc oncogenes: identification and localization in acute leukemia virus transformants and bursal lymphoma cell lines.Stephan Hann, Holly D. Abrams, Larry R. Rohrschneider — 1983
• Germ-line transmission of a c-abl mutation produced by targeted gene disruption in ES cells.Pamela L. Schwartzberg, Stephen P. Goff, Elizabeth J. Robertson — 1989
• Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vectorElizabeth J. Robertson, Allan Bradley, Michael R. Kuehn — 1986
• Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.Patricia S. Thomas — 1980

Cited by

• Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection.正江 木下, ふくみ 斎藤 — 1990
• Gene targeting in embryonic stem cells.Ramiro Ramírez‐Solis, Ann C. Davis, Allan Bradley — 1993
• Enhanced selection for homologous-recombinant embryonic stem cell clones with a neomycin phosphotransferase gene in antisense orientationBoris V. Skryabin, Claudia Schmauss — 2004
• Analysis of R-Ras signalling pathways.Annette J. Self, Emmanuelle Caron, Hugh F. Paterson — 2001
• myc family oncogenes in the development of normal and neoplastic cells.Ronald A. DePinho, Nicole Schreiber‐Agus, Frederick W. Alt — 1991
• Low level of Hox1.3 gene expression does not preclude the use of promoterless vectors to generate a targeted gene disruption. offLucie Jeannotte, Jenny Ruiz, Elizabeth J. Robertson — 1991
• Episome-generated N-myc antisense RNA restricts the differentiation potential of primitive neuroectodermal cell linesLuke Whitesell, A Rosolen, L M Neckers — 1991
• Adenosine deaminase deficiency: a model system for human somatic cell gene correction therapy.M.A. Vega — 1992
• Gene targeting in normal somatic cells: inactivation of the interferon–γ receptor in myoblastsMaría L. Arbonés, Harry A. Austin, Daniel J. Capon — 1994
• Targeted gene disruption of the endogenous c-abl locus by homologous recombination with DNA encoding a selectable fusion protein.Pam Schwartzberg, Elizabeth J. Robertson, Stephen P. Goff — 1990
• Myc represses primitive endoderm differentiation in pluripotent stem cellsKeriayn N. Smith, Amar M. Singh, Stephen Dalton — 2010
• Modifying the Mouse: Design and DesireAllan Bradley, Paul Hasty, Ann C. Davis — 1992
• Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene.Jean Charron, Barbara A. Malynn, Peter Fisher — 1992
• Modifying the mammalian genome by gene targeting.Allan Bradley — 1991
• Gene targeting in murine embryonic stem cells: introduction of specific alterations into the mammalian genome.Suzanne L. Mansour — 1990
• Modification of the apolipoprotein B gene in HepG2 cells by gene targeting.Robert V. Farese, L. M. Flynn, Stephen G. Young — 1992
• Genome manipulation in embryonic stem cells.Janet Rossant, Cecilia B. Moens, András Nagy — 1993
• Therapeutic gene targetingRafael J. Yáñez‐Muñoz, ACG Porter — 1998
• The MYCN oncogene and differentiation in neuroblastoma.Ulrica Westermark, Margareta Wilhelm, Anna Frenzel — 2011
• Prospects for homologous recombination in human gene therapyM.A. Vega — 1991

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