Spinal cord contusion models.
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Summary
The MASCIS Impactor is a well-standardized rat spinal cord contusion model that produces very consistent graded spinal cord damage that linearly predicts 24-h lesion volumes, 6-week white matter sparing, and locomotor recovery in rats.
- Type
- review
- Published
- 2002-01-01
- Cited by
- 297
- References
- 348
- OpenAlex
- https://openalex.org/W1779982979
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:34390776
Keywords
Spinal cord, Medicine, Spinal cord injury, Anesthesia, White matter
References
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- Ultrastructural appearances of the spinal microvasculature between 12 hours and 5 days after impact injury
- The pathophysiology of spinal cord trauma
- Involvement of metabotropic glutamate receptors in excitatory amino acid and GABA release following spinal cord injury in rat
- Alterations in AMPA Receptor Subunit Expression after Experimental Spinal Cord Contusion Injury
- Strain and Model Differences in Behavioral Outcomes after Spinal Cord Injury in Rat
- Methylprednisolone and neurological function 1 year after spinal cord injury. Results of the National Acute Spinal Cord Injury Study.
- Reduction of Pathological and Behavioral Deficits Following Spinal Cord Contusion Injury with the Selective Cyclooxygenase-2 Inhibitor NS-398
- 4‐Aminopyridine Improves Pulmonary Function in Quadriplegic Humans with Longstanding Spinal Cord Injury
- Cellular Localization of Tumor Necrosis Factor-α Following Acute Spinal Cord Injury in Adult Rats
- Reversible spinal cord trauma in cats. Additive effects of direct pressure and ischemia.
Cited by
- Imaging Studies of the Canine Cervical Vertebral Venous Plexus
- Characterization of Graded MASCIS Contusion Spinal Cord Injury using Somatosensory Evoked Potentials
- Spatio-Temporal Progression of Grey and White Matter Damage Following Contusion Injury in Rat Spinal Cord
- Novel aspects of spinal cord evoked potentials (SCEPs) in the evaluation of dorso-ventral and lateral mechanical impacts on the spinal cord
- X-irradiation reduces lesion scarring at the contusion site of adult rat spinal cord.
- CNS injury biomechanics and experimental models.
- Spinal Cord Control of Ejaculatory Reflexes in Male Rats
- Animal Studies in Spinal Cord Injury: A Systematic Review of Methylprednisolone
- Characterising changes in pathology and function in clinically relevant models of spinal cord injury and using chondroitinase ABC gene therapy to promote repair
- Efeitos funcionais da terapia autóloga de células-tronco derivadas da medula óssea (Cd45+ e Cd34-) no trauma raquimedular agudo nos murinos: sedentários e treinados físicos
- Diffusion Tensor Imaging as a Predictor of Locomotor Function after Experimental Spinal Cord Injury and Recovery
- The Effects of Age on the Morphometry of the Cervical Spinal Cord and Spinal Column in Adult Rats: An MRI‐Based Study
- Acute Traumatic Spinal Cord Injury Induces Glial Activation in the Cynomolgus Macaque (Macaca fascicularis)
- Treadmill step training promotes spinal cord neural plasticity after incomplete spinal cord injury
- The spinal locomotor CPG: a target after spinal cord injury.
- Efeito da injeção intratecal de células tronco do cordão umbilical humano na lesão isquêmica da medula espinhal em ratos
- Contuse lesion of the rat spinal cord of moderate intensity leads to a higher time-dependent secondary neurodegeneration than severe one. An open-window for experimental neuroprotective interventions.
- On CNS injury and olfactory ensheathing cell engraftment strategies
- Novel Use of Dual Anti-Inflammatory Therapy to Overcome Drug Resistance and Improve Functional Recovery Following Spinal Cord Injury
- The neuroprotective actions of quercetin
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