Circulating Branched-chain Amino Acid Concentrations Are Associated with Obesity and Future Insulin Resistance in Children and Adolescents
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Summary
BCAAs are elevated in adults with diet‐induced obesity, and are associated with their future risk of type 2 diabetes even after accounting for baseline clinical risk factors.
- Type
- article
- Published
- 2012-09-07
- Cited by
- 416
- References
- 46
- Access
- Open access
- OpenAlex
- https://openalex.org/W1764778685
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:20393447
Keywords
Medicine, Internal medicine, Insulin resistance, Endocrinology, Overweight
References
- Obesity reduces the bioavailability of nitric oxide in juveniles
- Oxidation of branched chain amino acids by isolated hearts and diaphragms of the rat. The effect of fatty acids, glucose, and pyruvate respiration.
- Protein turnover during puberty in normal children.
- Protein metabolism in obesity: effects of body fat distribution and hyperinsulinemia on leucine turnover.
- Branched-chain amino acids and brain function.
- Observations of branched-chain amino acid administration in humans.
- Hormonal and signaling role of branched-chain amino acids.
- Amino acid balance across tissues of the forearm in postabsorptive man. Effects of insulin at two dose levels.
- Skeletal muscle phosphocreatine recovery after submaximal exercise in children and young and middle-aged adults.
- Insulin resistance of puberty: a defect restricted to peripheral glucose metabolism.
- 3-Hydroxyanthranilic Acid Is an Efficient, Cell-derived Co-antioxidant for α-Tocopherol, Inhibiting Human Low Density Lipoprotein and Plasma Lipid Peroxidation*
- Differential Metabolic Impact of Gastric Bypass Surgery Versus Dietary Intervention in Obese Diabetic Subjects Despite Identical Weight Loss
- Kynurenines and the respiratory parameters on rat heart mitochondria.
- Skeletal muscle mitochondrial function is associated with longitudinal growth velocity in children and adolescents.
- Glucagon-stimulating activity of 20 amino acids in dogs.
- The global spread of type 2 diabetes mellitus in children and adolescents.
- Statistical methods for assessing agreement between two methods of clinical measurement.
- Development of Questionnaire to Examine Relationship of Physical Activity and Diabetes in Pima Indians
- The Glial Glutamate Transporter 1 (GLT1) Is Expressed by Pancreatic β-Cells and Prevents Glutamate-induced β-Cell Death*
- Metabolite Profiles and the Risk of Developing Diabetes
Cited by
- Insulin resistance and the metabolism of branched-chain amino acids
- Akne und Ernährung
- Is Leucine Intake Associate with Enhanced Muscle Protein Synthesis and Attenuated Muscle Protein Breakdown
- The importance of dietary protein for muscle health in inactive, hospitalized older adults
- Migraine and obesity: metabolic parameters and response to a weight loss programme
- Cross-sectional examination of metabolites and metabolic phenotypes in uremia
- Metabolomic signatures in lipid-loaded HepaRGs reveal pathways involved in steatotic progression
- Metabolomic profiles and childhood obesity
- An Overview of the Role of Metabolomics in the Identification of Dietary Biomarkers
- Branched-chain amino acids as biomarkers in diabetes.
- Metabolomic analysis reveals decreased skeletal muscle amino acid content and altered fatty acid handling in obese humans
- Global deletion of BCATm increases expression of skeletal muscle genes associated with protein turnover.
- Metabolomics for Improved Understanding and Prediction of Cardiometabolic Diseases—Recent Findings from Human Studies
- Association of branched-chain amino acids with coronary artery disease: A matched-pair case-control study.
- Lower Preprandial Insulin and Altered Fuel Use in HIV/Antiretroviral-Exposed Infants in Cameroon.
- Alterations of plasma metabolite profiles related to adipose tissue distribution and cardiometabolic risk.
- Serum and adipose tissue amino acid homeostasis in the metabolically healthy obese.
- Associations of cord blood metabolites with early childhood obesity risk
- Personalized nutrition and obesity
- Long-term commercial cow's milk consumption and its effects on metabolic parameters associated with obesity in young mice.
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