Human proto‐oncogene c‐kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.
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Summary
The results suggest that p145c‐kit functions as a cell surface receptor for an as yet unidentified ligand, and carboxy‐ and amino‐terminal truncations that occurred during the viral transduction process are likely to have generated the transformation potential of v‐kit.
- Type
- article
- Published
- 1987-11-01
- Cited by
- 1,580
- References
- 4
- Access
- Open access
- OpenAlex
- https://openalex.org/W1752312133
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4310608
Keywords
Biology, Receptor tyrosine kinase, Tyrosine kinase, ROR1, Ligand (biochemistry)
References
Cited by
- Gene expression during oogenesis in mice.
- Expression of the colony-stimulating factor-1 receptor (c-fms proto-oncogene product) in the human uterus and placenta.
- Molecular bases of dominant negative and loss of function mutations at the murine c‐kit/white spotting locus: W37, Wv, W41 and W.
- The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus.
- Isolation and characterization of the alpha platelet-derived growth factor receptor from rat olfactory epithelium
- Gastrointestinal stromal tumors with exon 8 c-kit gene mutation might occur at extragastric sites and have metastasis-prone nature.
- Expression of the c-kit proto-oncogene and its ligand stem cell factor (SCF) in normal and malignant human testicular tissue.
- Characterization of c-kit-positive neurons in the dorsal root ganglion of mouse.
- Steel and c‐kit in the development of avian melanocytes: A study of normally pigmented birds and of the hyperpigmented mutant silky fowl
- Human Stem Cell Factor Dimer Forms a Complex with Two Molecules of the Extracellular Domain of Its Receptor, Kit (*)
- Expression and regulation of c-kit receptor and response to stem cell factor in childhood malignant T-lymphoblastic cells
- Role of C‐kitreceptor tyrosine kinase in development of oval cells in the rat 2‐acetylaminofluorene/partial hepatectomy model
- Tyrosine kinase oncogenes in normal hematopoiesis and hematological disease
- Identification of isoforms and RH mapping of canine KIT
- Functional and phenotypic characterization of cord blood and bone marrow subsets expressing FLT3 (CD135) receptor tyrosine kinase.
- Developmental model for the pathogenesis of testicular carcinoma in situ: genetic and environmental aspects.
- Expression of c-Kit receptor tyrosine kinase and effect on beta-cell development in the human fetal pancreas.
- Elevation of serum stem‐cell factor in postoperative biliary atresia
- Analyses of novel prognostic factors in neuroblastoma patients.
- Positive and negative signaling in B lymphocytes.
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