In vivo activation of antigen-specific CD4 T cells.
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Summary
Inflammation enhances in vivo T cell activation by stimulating dendritic cells to migrate to the T cell areas and display stable peptide-MHC complexes and costimulatory ligands, which produces an increased number of specific T cells capable of producing effector lymphokines throughout the body.
- Type
- review
- Published
- 2001-04-01
- Cited by
- 554
- References
- 102
- OpenAlex
- https://openalex.org/W1687035583
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:8645892
Keywords
Biology, Lymphokine, Antigen-presenting cell, Cell biology, Antigen
References
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- Inflammatory cytokines enhance the in vivo clonal expansion and differentiation of antigen-activated CD4+ T cells.
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- Chemokines and cell migration in secondary lymphoid organs.
- Following the development of a CD4 T cell response in vivo: from activation to memory formation.
- Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis.
Cited by
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- Autoreactivity, dynamic tuning and selectivity.
- Nippostrongylus brasiliensis Can Induce B7-Independent Antigen-Specific Development of IL-4-Producing T Cells from Naive CD4 T Cells In Vivo1
- Differential Antigen Presentation Regulates the Changing Patterns of CD8+ T Cell Immunodominance in Primary and Secondary Influenza Virus Infections
- APC-targeted immunization for the treatment of HIV-1
- Mesenteric Th1 polarization and monocyte TNF‐α production: First steps to systemic inflammation in rats with cirrhosis
- Krüppel-Like Factor 2, a Novel Immediate-Early Transcriptional Factor, Regulates IL-2 Expression in T Lymphocyte Activation1
- Induction of human CD4+ regulatory T cells by mycophenolic acid‐treated dendritic cells
- Immunomodulatory effect of pneumolysin upon CD4 T cells
- On the trail of arthritogenic T cells.
- Lactoferrin Augmentation of the BCG Vaccine Leads to Increased Pulmonary Integrity
- Is central nervous system an immune-privileged site?
- Fas Ligand-exprimierende humane dendritische Zellen zur Induktion von T-Zelltoleranz: Phänotypische und funktionelle Charakterisierung
- THE INFLUENCE OF SELENIUM STATUS ON IMMUNE FUNCTION AND ANTIOXIDANT STATUS IN THE HORSE
- Factors mediating successful oral vaccination with lipid-encapsulated Mycobacterium bovis BCG
- The delayed type hypersensitivity response: a model for studying the defects in skin immunity in the old
- A Role for Eosinophils in Adaptive Humoral Immunity
- Regulation of natural killer and cd4+T cell function by NKG2 C-type lectin-like receptors
- Contrasting roles of dendritic cells and B cells in the immune control of Epstein-Barr virus.
- Molecular genetic dissection of the zebrafish olfactory system.
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