Effect of combined treatment with the epirubicin‐incorporating micelles (NC‐6300) and 1,2‐diaminocyclohexane platinum (II)‐incorporating micelles (NC‐4016) on a human gastric cancer model
Explore this paper's citation graph
Summary
The combined use of the micelles was associated with remarkable efficacy and favorable toxicities in the human gastric cancer model, and warrants the conduct of clinical trials.
- Type
- article
- Published
- 2014-07-01
- Cited by
- 36
- References
- 37
- Access
- Open access
- OpenAlex
- https://openalex.org/W1679811816
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:22227177
Keywords
Epirubicin, Oxaliplatin, Micelle, In vivo, Pharmacology
References
- A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.
- Phase I Study of NK012, a Novel SN-38–Incorporating Micellar Nanoparticle, in Adult Patients with Solid Tumors
- Cisplatin-incorporating polymeric micelles (NC-6004) can reduce nephrotoxicity and neurotoxicity of cisplatin in rats
- Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival
- Synergistic antitumor activity of the novel SN‐38‐incorporating polymeric micelles, NK012, combined with 5‐fluorouracil in a mouse model of colorectal cancer, as compared with that of irinotecan plus 5‐fluorouracil
- Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
- Nanotechnology-based combinational drug delivery: an emerging approach for cancer therapy.
- Combination antitumor effects of micelle-loaded anticancer drugs in a CT-26 murine colorectal carcinoma model.
- Polymer-Caged Nanobins for Synergistic Cisplatin-Doxorubicin Combination Chemotherapy
- Multimodal assessment of painful peripheral neuropathy induced by chronic oxaliplatin-based chemotherapy in mice
- Preparation and biological properties of dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt)-loaded polymeric micelles.
- Development and biological analysis of peritoneal metastasis mouse models for human scirrhous stomach cancer
- Phase II study of NK105, a paclitaxel-incorporating micellar nanoparticle, for previously treated advanced or recurrent gastric cancer
- Synergistic antitumor activity of the SN‐38‐incorporating polymeric micelles NK012 with S‐1 in a mouse model of non‐small cell lung cancer
- Preclinical and clinical studies of NK012, an SN-38-incorporating polymeric micelles, which is designed based on EPR effect.
- Optimization of (1,2-diamino-cyclohexane)platinum(II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity.
- Improved anti‐tumor activity of stabilized anthracycline polymeric micelle formulation, NC‐6300
- NC‐6300, an epirubicin‐incorporating micelle, extends the antitumor effect and reduces the cardiotoxicity of epirubicin
- Co-delivery of daunomycin and oxaliplatin by biodegradable polymers for safer and more efficacious combination therapy.
- Antiproliferative effect of silybin on gynaecological malignancies: synergism with cisplatin and doxorubicin.
Cited by
- Assessment of antitumor activity and acute peripheral neuropathy of 1,2-diaminocyclohexane platinum (II)-incorporating micelles (NC-4016)
- Micellar carriers for the delivery of multiple therapeutic agents.
- Sonodynamic Therapy Based on Combined Use of Low Dose Administration of Epirubicin-Incorporating Drug Delivery System and Focused Ultrasound.
- Progress of drug-loaded polymeric micelles into clinical studies.
- Noncovalent interaction-assisted polymeric micelles for controlled drug delivery.
- Application of the combination index integrated with confidence intervals to study the toxicological interactions of antibiotics and pesticides in Vibrio qinghaiensis sp.-Q67.
- Plasma and cellular pharmacokinetic considerations for the development and optimization of antitumor block copolymer micelles
- Effects of Treatment with Platinum Azidothymidine and Azidothymidine on Telomerase Activity and Bcl-2 Concentration in Hepatocellular Carcinoma- Induced Rats
- The drug discovery by nanomedicine and its clinical experience.
- Advances in drug delivery system for platinum agents based combination therapy
- Utility of epirubicin‐incorporating micelles tagged with anti‐tissue factor antibody clone with no anticoagulant effect
- Clinical Translation of Nanomedicine
- Anticancer agent-incorporating immunomicelles
- Targeted Drug Delivery with Polymers and Magnetic Nanoparticles: Covalent and Noncovalent Approaches, Release Control, and Clinical Studies.
- Multifunctional biodegradable polymeric nanocarriers: Design, synthesis, and applications in targeted tumor therapy
- Investigational nanomedicines in 2016: a review of nanotherapeutics currently undergoing clinical trials.
- Leveraging Physiology for Precision Drug Delivery
- Quantitative Characterization of the Toxicities of Cd-Ni and Cd-Cr Binary Mixtures Using Combination Index Method
- Clinical application of polymeric micelles for the treatment of cancer
- Polymeric micelles for targeted tumor therapy of platinum anticancer drugs
Related papers
- Oxaliplatin─Based Chemotherapy の腹膜播種を伴うStage IV 大腸癌に対する効果
- Clinical Features of Oxaliplatin-induced Hypersensitivity Reactions in Chinese Patients: A Retrospective Multicenter Analysis
- 03:00 PM Abstract No. 316 Morphology, loadability, and releasing profiles of CalliSpheres microspheres in delivering oxaliplatin: an in vitro study
- mFOLFOX6/Bevacizumabによる治療開始後に脾臓が増大しOxaliplatin休薬により脾臓が縮小した大腸癌の2 例
- A prospective randomized trial comparing epirubicin monochemotherapy to two fluorouracil, cyclophosphamide, and epirubicin regimens differing in epirubicin dose in advanced breast cancer patients. The French Epirubicin Study Group.
- In Vitro Chemosensitivity Test for Gastric Cancer Specimens Predicts Effectiveness of Oxaliplatin and 5-Fluorouracil.
- Oxaliplatin-induced severe anaphylactic reactions in metastatic colorectal cancer: Case series analysis
- Efficacy and Safety Analysis of Oxaliplatin-based Chemotherapy for Advanced Gastric Cancer.
- Comparison on the clinical curative effect and adverse reactions of the domestic vs.imported oxaliplation
- Effects of epirubicin combined with 5-fluorouracil and oxaliplatin on proliferation and apoptosis of human hepatoma HepG2 cells