Messenger RNA expression of the immunosuppressive cytokine IL-10 in human gliomas.
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Summary
It is suggested that IL-10 may contribute to the progression of astrocytomas by suppressing the patient's immune response, whereas IL-6 provides an additional growth advantage.
- Type
- article
- Published
- 1995-02-01
- Cited by
- 186
- References
- 25
- Access
- Open access
- OpenAlex
- https://openalex.org/W1672419507
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25029637
Keywords
Autocrine signalling, Glioma, Biology, Cytokine, Immune system
References
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- Cytokine gene expression by human gliomas.
- Interleukin‐10 production by human carcinoma cell lines and its relationship to interleukin‐6 expression
- A new view of prostaglandin E regulation of the immune response.
- Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin
- Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas
- Modulation of T-cell function by gliomas.
- Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI.
- Interleukin‐6 (IL‐6) functions as an in vitro autocrine growth factor in renal cell carcinomas
- The role of IL-10 in crossregulation of TH1 and TH2 responses.
- Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dememtia
- Presence of interleukin 10 (IL-10) in the ascites of patients with ovarian and other intra-abdominal cancers.
- Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones
- Analysis of cytokine mRNA and DNA: detection and quantitation by competitive polymerase chain reaction.
- Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression
- Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.
- Involvement of nitric oxide on the cytokine induced growth of glial cell.
Cited by
- Interleukin-6-producing Cells in a Human Glioblastoma Cell Line are not Affected by Ionizing Radiation
- B7-H1 Expression on Non-Small Cell Lung Cancer Cells and Its Relationship with Tumor-Infiltrating Lymphocytes and Their PD-1 Expression
- Immunotherapy of glioblastoma multiforme
- An Update of Vaccine Therapy and Other Immunotherapeutic Approaches for Glioblastoma
- Basic concepts in glioma immunology.
- Immune responses in glioblastoma: an avenue to effective cancer therapy or a mere epiphenomenon?
- Antigen-receptor gene-modified T cells for treatment of glioma.
- CNTF and its Receptor Subunits in Human Gliomas
- Mechanisms of immune evasion by gliomas.
- Expression of matrix metalloproteinases in human glioma cell lines in the presence of IL-10
- Down-regulation of transforming growth factor-β and interleukin-10 secretion from malignant glioma cells by cytokines and anticancer drugs
- T cell immunity in patients with malignant glioma: recent progress in dendritic cell-based immunotherapeutic approaches.
- Protective and Pathological Immune Responses in the CNS
- Perspectives in Post-Transplantation Immunotherapy in Breast Cancer
- Characteristics of Human Cytomegalovirus specific T-Cells in Glioblastoma Multiforme
- AML1–ETO downregulates the granulocytic differentiation factor C/EBPα in t(8;21) myeloid leukemia
- Immunosuppressive Mechanisms of Malignant Gliomas: Parallels at Non-CNS Sites
- Inverse modulation of IL‐10 and IL‐12 in the blood of women with preneoplastic lesions of the uterine cervix
- Interleukin 10 production by human melanoma.
- T cell adoptive immunotherapy of newly diagnosed gliomas.
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