Defying death after DNA damage
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Summary
This work addresses some fundamental questions that arise from the model of apoptosis that frequently triggers death by apoptosis and the consequences of failure to initiate apoptosis in response to DNA damage.
- Type
- review
- Published
- 2000-10-12
- Cited by
- 803
- References
- 78
- OpenAlex
- https://openalex.org/W1656708631
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4381950
Keywords
DNA damage, Apoptosis, Programmed cell death, Effector, Apoptosome
References
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- BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer.
- Yeast as a tool for apoptosis research.
- p53 and E2F-1 cooperate to mediate apoptosis.
Cited by
- Overexpression of α7 nicotinic acetylcholine receptor prevents G1‐arrest and DNA fragmentation in PC12 cells after hypoxia
- Pancreas preservation by the 2-layer cold storage method before islet isolation protects isolated islets against apoptosis through the mitochondrial pathway.
- Annexins: Key Regulators of Haemostasis, Thrombosis, and Apoptosis
- Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 7- and 5-, 6-, 8-positions.
- Discovery and structure-activity relationship of 2-phenyl-oxazole-4-carboxamide derivatives as potent apoptosis inducers.
- DNA damage repair and genetic polymorphisms: assessment of individual sensitivity and repair capacity.
- DNA Repair Mechanisms in Huntington’s Disease
- Mathematical model of adult stem cell regeneration with cross-talk between genetic and epigenetic regulation
- Mismatch repair during homologous and homeologous recombination.
- Intervertebral disc degeneration: the role of the mitochondrial pathway in annulus fibrosus cell apoptosis induced by overload.
- XRCC1, un élément clef de la réparation des dommages de l'ADN couplée à la réplication
- Envolvimento do dano ao DNA e estresse oxidativo no transtorno bipolar e no uso de metilfenidato
- Pathways of myocyte death: implications for development of clinical laboratory biomarkers.
- siRNA screening of the kinome identified Aurora A kinase as a therapeutic target gene in cervical cancer
- DNA damage responses in human pluripotent stem cells
- Intrinsic Apoptotic Pathway: Effects of Calcium on Murine Cytochrome C Release in Brain and Liver Mitochondria
- Interstrand Crosslinks - Induction and repair
- EFFETS DES RADIATIONS IONISANTES SUR DES COMPLEXES ADN-PROTÉINE
- The Circadian Clock in Cancer Development and Therapy
- Patterns of post-translational histone modifications, chromatin condensation and DNA fragmentation during apoptosis
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