Genistein, a specific inhibitor of tyrosine-specific protein kinases.
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Summary
Genistein inhibited the EGF-stimulated increase in phosphotyrosine level in A431 cells and scarcely inhibited the enzyme activities of serine- and threonine-specific protein kinases such as cAMP-dependent protein kinase, phosphorylase kinases, and the Ca2+/phospholipid-dependent enzymeprotein kinase C.
- Type
- article
- Published
- 1987-04-25
- Cited by
- 3,814
- References
- 0
- Access
- Open access
- OpenAlex
- https://openalex.org/W1656644300
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24903943
Keywords
Mitogen-activated protein kinase kinase, Tyrosine kinase, Platelet-derived growth factor receptor, Biology, MAP2K7
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