Serial MRI after transient focal cerebral ischemia in rats: dynamics of tissue injury, blood-brain barrier damage, and edema formation.
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Summary
Reperfusion after short periods of ischemia appears to be mainly complicated by secondary ischemic damage as shown by the delayed recurrence of the DWI lesions, whereas BBB damage associated with vasogenic edema becomes a dominant factor with longer occlusion times (2.5 hours).
- Type
- article
- Published
- 2000-08-01
- Cited by
- 369
- References
- 55
- Access
- Open access
- OpenAlex
- https://openalex.org/W1655344346
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:414594
Keywords
Medicine, Ischemia, Edema, Magnetic resonance imaging, Occlusion
References
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- Morphological Manifestations of Reperfusion Injury in Brain a
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- Temporal and anatomical variations of brain water apparent diffusion coefficient in perinatal cerebral hypoxic‐ischemic injury: Relationships to cerebral energy metabolism
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- Role of oxidants in ischemic brain damage.
- Longitudinal magnetic resonance imaging study of perfusion and diffusion in stroke: Evolution of lesion volume and correlation with clinical outcome
Cited by
- Hyperbaric oxygen reduces blood-brain barrier damage and edema after transient focal cerebral ischemia
- Time Is Brain—Quantified
- Bilateral cortical hyperactivity detected by fMRI associates with improved motor function following intravenous infusion of mesenchymal stem cells in a rat stroke model.
- Synergic Effects of Rehabilitation and Intravenous Infusion of Mesenchymal Stem Cells After Stroke in Rats
- Experimental stroke research: the contributions of in vivo MRI.
- Temporal evolution of apparent diffusion coefficient and T2 value following transient focal cerebral ischemia in gerbils.
- Development of imaging methods for the lithium-pilocarpine model of epilepsy
- Lokalisierung und Charakterisierung Foxp3+ regulatorischer T-Zellen bis zu 30 Tage nach mechanischer und ischämischer Läsion des Gehirns
- Imaging of pediatric stroke
- Application of combined magnetic resonance imaging and histopathologic and functional studies for evaluation of aminoguanidine following traumatic brain injury in rats.
- Granulocyte-macrophage colony-stimulating factor-transfected bone marrow stromal cells for the treatment of ischemic stroke
- Neonatal cardiac surgery: Preventing collateral damage
- Surgical decompression for space-occupying hemispheric infarction
- Intracerebral injection of human mesenchymal stem cells impacts cerebral microvasculature after experimental stroke: MRI study
- Imaging in Acute Stroke – a Personal View*
- Imaging cell death in vivo.
- Blood-brain barrier leakage after transient cerebral ischemia
- A Reproducible and Translatable Model of Focal Ischemia in the Visual Cortex of Infant and Adult Marmoset Monkeys
- CNS injury, γ1 laminin, and its KDI peptide
- Use of normobaric and hyperbaric oxygen in acute focal cerebral ischemia – a preclinical and clinical review
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