Dietary Iron Supplementation Enhances DSS-Induced Colitis and Associated Colorectal Carcinoma Development in Mice
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Summary
Dietary iron can enhance UC and its associated carcinogenesis by augmenting oxidative and nitrosative stress and the findings have implications for the management of human UC.
- Type
- article
- Published
- 2002-06-01
- Cited by
- 197
- References
- 38
- OpenAlex
- https://openalex.org/W1591222484
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25746895
Keywords
Ulcerative colitis, Anemia, Gastroenterology, Oxidative stress, Internal medicine
References
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- Role of oxidative DNA damage in cancer initiation and promotion.
- Iron Supplementation May Aggravate Inflammatory Status of Colitis in a Rat Model
- Characterization of early pulmonary hyperproliferation and tumor progression and their inhibition by black tea in a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis model with A/J mice.
- A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice.
- Oxidative damage and defense.
- Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis.
- Iron metabolism in inflammation.
- Significance and detection of dysplasia in chronic colitis
- Cancer morbidity in ulcerative colitis.
- Oxygen radicals in ulcerative colitis.
- Oral or parenteral iron treatment in chronic ulcerative colitis?
- Colon cancer, dysplasia, and surveillance in patients with ulcerative colitis. A critical review.
- Survival with Colorectal Cancer in Ulcerative Colitis A Study of 102 Cases
- The pattern of cell proliferation in neoplastic and nonneoplastic lesions of ulcerative colitis
- Most free‐radical injury is iron‐related: It is promoted by iron, hemin, holoferritin and vitamin c, and inhibited by desferoxamine and apoferritin
- Colorectal carcinoma associated with ulcerative colitis: a study of prognostic indicators.
- Iron homeostasis, oxidative stress, and DNA damage.
- Moderate elevation of body iron level and increased risk of cancer occurrence and death
Cited by
- Diagnosis and management of iron deficiency anemia in patients with IBD
- Iron, microbiota and colorectal cancer
- Induced nitric oxide synthase as a major player in the oncogenic transformation of inflamed tissue.
- Emerging therapeutic options for celiac disease: potential alternatives to a gluten-free diet.
- Stimulating erythropoiesis in inflammatory bowel disease associated anemia.
- The effects of dietary iron concentration on colonic inflammation
- A role for iron in oesophageal adenocarcinoma
- Iron therapy in inflammatory bowel disease : effects on oxidative stress and disease activity
- Responses of the gut microbiota to supplementary iron: a survey at the host-microbial interface
- Anaemia in inflammatory bowel disease. A complication frequently unknown: "practical approach for the gastroenterologist"
- Treatment of iron deficiency anemia associated with gastrointestinal tract diseases.
- Preventive Therapy of Experimental Colitis with Selected iron Chelators and Anti-oxidants
- Crucial Role of FLVCR1a in the Maintenance of Intestinal Heme Homeostasis
- [Pathophysiological-based diagnosis and therapy of iron-deficient anaemia in inflammatory bowel disease].
- Ferrous sulfate, but not iron polymaltose complex, aggravates local and systemic inflammation and oxidative stress in dextran sodium sulfate-induced colitis in rats
- Suppression of colitis-related mouse colon carcinogenesis by a COX-2 inhibitor and PPAR ligands
- Iron and health
- State of the iron: how to diagnose and efficiently treat iron deficiency anemia in inflammatory bowel disease.
- Phosphoinositide 3-Kinase Signaling Mediates □-Catenin Activation in Intestinal Epithelial Stem and Progenitor Cells in Colitis
- Expression of iron absorption genes in mouse large intestine
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