Hormonal regulation of calcium homeostasis in two breeds of dogs during growth at different rates.
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Summary
It is suggested that in GD, increased calcitonin levels and/or a relative deficiency in 24,25(OH)2D3 at the growth-plate level may both be responsible for the retarded maturation of chondrocytes, resulting in retained cartilage cones and osteochondrosis, and this may be a pathophysiological factor for the increased susceptibility of large breed dogs to developing skeletal disorders.
- Type
- article
- Published
- 2003-06-01
- Cited by
- 54
- References
- 64
- OpenAlex
- https://openalex.org/W1586336932
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:45044601
Keywords
Internal medicine, Endocrinology, Breed, Homeostasis, Parathyroid hormone
References
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- Effect of diets with different calcium and phosphorus contents on the skeletal development and blood chemistry of growing great danes
- Morphological Findings in Young Dogs Chronically Fed a Diet Containing Excess Calcium
- Vitamin D-independent regulation of calcium and phosphate absorption.
- Variability of calcium absorption.
- Assay of circulating 1,25-dihydroxyvitamin D involving a novel single-cartridge extraction and purification procedure.
- Calcium metabolism in Great Dane dogs fed diets with various calcium and phosphorus levels.
- Vitamin D and intestinal calcium transport: facts, speculations and hypotheses.
- EFFECT OF GROWTH HORMONE ON TUBULAR TRANSPORT OF PHOSPHATE IN NORMAL AND PARATHYROIDECTOMIZED DOGS.
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- A RADIOGRAPHIC STUDY ON THE DEVELOPMENT OF THE ANTEBRACHIUM IN GREAT DANE PUPS, RAISED UNDER STANDARDIZED CONDITIONS
- Effect of 24,25-dihydroxyvitamin D3 on 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3] metabolism in vitamin D-deficient rats infused with 1,25-(OH)2D3.
- Calcium and vitamin D metabolism in acromegaly.
- Regulation of sterol 27-hydroxylase and an alternative pathway of bile acid biosynthesis in primary cultures of rat hepatocytes.
- Effects of growth hormone administration on vitamin D metabolism and vitamin D receptors in the pig.
- Consequences of vitamin D receptor regulation for the 1,25-dihydroxyvitamin D3-induced 24-hydroxylase activity in osteoblast-like cells: initiation of the C24-oxidation pathway.
- Metabolic clearance rate and production rate of calcitriol in uremia.
- Effects of exogenous growth hormone on bone mineralization and remodeling and on plasma calcitriol in intact pigs.
Cited by
- Do large dogs die young?
- Utfodringens betydelse för osteokondros hos hund
- Height variation in the canine species as a model to identify new targets in bone regenerative medicine.
- Development of medial coronoid disease in Labrador retrievers: Diagnostic and pathogenic studies
- Breed dependency of reference intervals for plasma biochemical values in cats.
- Nutrition and the skeletal health of dogs and cats
- Expression Profiles of the Insulin-like Growth Factor System Components in Liver Tissue during Embryonic and Postnatal Growth of Erhualian and Yorkshire Reciprocal Cross F1 Pigs
- Surgical Correction of Patellar Luxation in a Rabbit
- Calcium-excess causes subclinical changes of bone growth in Beagles but not in Foxhound-crossbred dogs, as measured in X-rays.
- Influence of UVB exposure on the vitamin D status and calcium homoeostasis of growing sheep and goats.
- Factors that modify the effect of excess calcium on skeletal development in puppies.
- Effects of Feeding Intensity and Ca:P Ratio on Foot Welfare in Blue Foxes (Vulpes lagopus)
- Basal plasma concentrations of routine variables and packed cell volume in clinically healthy adult small-sized dogs: effect of breed, body weight, age, and gender, and establishment of reference intervals.
- Calcium and vitamin d metabolism, deficiency, and excess.
- Pharmacogenetic and Metabolic Differences Between Dog Breeds: Their Impact on Canine Medicine and the Use of the Dog as a Preclinical Animal Model
- Role of the GH/IGF-1 axis in lifespan and healthspan: lessons from animal models
- Age-related cataract in dogs: a biomarker for life span and its relation to body size
- Composição nutricional e avaliação de rótulo de rações secas para cães comercializadas em Jaboticabal-SP
- Intraspecies disparity in growth rate is associated with differences in expression of local growth plate regulators.
- Growth Hormone Stimulates Bone Healing in a Critical-sized Bone Defect Model
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