Signal transduction pathways and their relevance in human astrocytomas
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Summary
Elucidating the role of signal transduction pathways in GBMs is of major clinical importance, as thesenovel molecularly-targeted agents may prove of use inthe clinical management of GBMs in the future.
- Type
- review
- Published
- 1997-12-01
- Cited by
- 67
- References
- 239
- OpenAlex
- https://openalex.org/W1584895714
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24847810
Keywords
Signal transduction, Platelet-derived growth factor receptor, Receptor, Growth factor receptor, Epidermal growth factor receptor
References
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- WILMS’ TUMOR-1 (WT1) PROTEIN EXPRESSION IN GLIOMA CELLS ACTUATES CELLULAR INVASIVENESS- IDENTIFYING ITS TARGET GENES
- Aspects of Tumour Targeting : Preclinical Studies on Human Malignant Cells in vitro
- Biological horizons for targeting brain malignancy.
- Growth Factors in Glioma Angiogenesis: FGFs, PDGF, EGF, and TGFs
- Oncolytic adenoviral therapy for glioblastoma multiforme.
- Biological Mechanisms of Glioma Invasion and Potential Therapeutic Targets
- Antiangiogenic Drugs Synergize with a Membrane Macrophage Colony-Stimulating Factor-Based Tumor Vaccine to Therapeutically Treat Rats with an Established Malignant Intracranial Glioma1
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- Ceramide levels are inversely associated with malignant progression of human glial tumors
- Class III β-Tubulin Isotype: A Key Cytoskeletal Protein at the Crossroads of Developmental Neurobiology and Tumor Neuropathology
- Cooperative translational control of gene expression by Ras and Akt in cancer.
- Novel medical therapeutics in glioblastomas, including targeted molecular therapies, current and future clinical trials.
- Differential transformation capacity of neuro-glial progenitors during development
- Anti-Angiogenic Drugs Syngerize with a Membrane Macrophage Colony Stimulating Factor Based Tumor Vaccine to Therapeutically Treat Rats with an Established Malignant Intracranial Glioma
- The 61 A/G EGF polymorphism is functional but is neither a prognostic marker nor a risk factor for glioblastoma.
- Angiogenesis and Anti-Angiogenic Molecularly Targeted Therapies in Malignant Gliomas
- Phorbol 12-myristate 13-acetate and serum synergize to promote rapamycin-insensitive cell proliferation via protein kinase C-eta
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