K‐ras mutations in mucinous ovarian tumors
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Summary
The authors looked for K‐ras point mutations at codons 12 and 13 in 95 mucinous ovarian neoplasms and the results were subsequently correlated with the clinicopathologic data.
- Type
- article
- Published
- 1997-04-15
- Cited by
- 243
- References
- 28
- Access
- Open access
- OpenAlex
- https://openalex.org/W1577974112
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:20533440
Keywords
Microdissection, Mucinous cystadenoma, Pathology, Point mutation, Mucinous carcinoma
References
- Benign, borderline and malignant serous cystadenomas of the ovary. A transmission and scanning electron microscopical study.
- Rapid detection of ras oncogenes in human tumors: applications to colon, esophageal, and gastric cancer.
- K-ras activation occurs frequently in mucinous adenocarcinomas and rarely in other common epithelial tumors of the human ovary.
- Mutation of K-ras protooncogene in human ovarian epithelial tumors of borderline malignancy.
- p53 and Ki-ras gene mutations in epithelial ovarian neoplasms.
- Current concepts in epithelial ovarian tumors: does benign to malignant transformation occur?
- Ovarian intraepithelial neoplasia demonstrated in patients with stage I ovarian carcinoma.
- Genetic alterations distinguish different types of ovarian tumors
- Frequency and spectrum of mutations at codons 12 and 13 of the c-K-ras gene in human tumors.
- Synchronous mucinous tumors of the appendix and the ovary associated with pseudomyxoma peritonei. A clinicopathologic study of six cases with comparative analysis of c-Ki-ras mutations.
- Metastases from Carcinomas of the Pancreas Simulating Primary Mutinous Tumors of the Ovary: A Report of Seven Cases
- Transition from benign to malignant epithelium in mucinous and serous ovarian cystadenocarcinoma.
- ras oncogenes in human cancer: a review.
- Mutation of K-ras protooncogene is associated with histological subtypes in human mucinous ovarian tumors.
- Oncogene detection at the single cell level.
Cited by
- Nouvelles perspectives et biomarqueurs dans le diagnostic et la prise en charge des tumeurs gynécologiques
- K-ras alterations in Danish ovarian tumour patients. From the Danish "Malova" Ovarian Cancer study.
- Oncogenic signaling pathways and deregulated target genes.
- Pulmonary mucinous cystadenoma: a rare benign tumor of the lung
- Animal models of ovarian cancer.
- Mucinous tumors of the ovary: a review.
- Current concepts in ovarian epithelial tumorigenesis: correlation between morphological and molecular data.
- Cancers de l’ovaire : la biologie moléculaire
- Identifying common genetic variants associated with disease risk and clinical outcome in epithelial ovarian cancer
- Pathobiology of ovarian carcinomas
- Anàlisi de la resposta als tractaments combinats amb cisplatí en el càncer d'ovari: Factors implicats en la quimioresistència
- Identification of the Rassf3 gene as a potential tumor suppressor responsible for the resistance to mammary tumor development in MMTV/neu transgenic mice
- FUNCTIONS OF THE HOMEOBOX GENE DLX4 IN CONTROLLING INFLAMMATORY SIGNALING AND METASTASIS OF EPITHELIAL OVARIAN CANCER
- Use of Ras-transformed human ovarian surface epithelial cells as a model for studying ovarian cancer.
- Ovarian cancer: pathology, biology, and disease models.
- Marker tumorali nel carcinoma ovarico
- Role of p53 and Rb in ovarian cancer.
- Endocervical‐like (Müllerian) mucinous borderline tumours of the ovary are frequently associated with the KRAS mutation
- Data set for reporting of ovary, fallopian tube and primary peritoneal carcinoma: recommendations from the International Collaboration on Cancer Reporting (ICCR)
- Que sait-on de la carcinogenèse ovarienne?
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