Role of chemotherapy for advanced/recurrent gastric cancer: an individual-patient-data meta-analysis.
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Summary
This meta-analysis of individual patient data shows that the additions of experimental chemotherapeutic agents to pre-existing control or standard regimens have produced a modest improvement in OS and PFS.
- Type
- review
- Published
- 2013-01-24
- Cited by
- 165
- References
- 62
- OpenAlex
- https://openalex.org/W1576469977
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25294906
Keywords
Medicine, Hazard ratio, Meta-analysis, Internal medicine, Chemotherapy
References
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- Treatment of patients with advanced gastric carcinoma with a 5‐fluorouracil‐based or a cisplatin‐based regimen
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- Fluorouracil, doxorubicin, and mitomycin combination versus PELF chemotherapy in advanced gastric cancer: a prospective randomized trial of the Italian Oncology Group for Clinical Research.
- Final results of a randomized phase III trial of docetaxel, carboplatin and 5FU versus epirubicin, cisplatin and 5FU for locally advanced gastric cancer
- FAMTX versus etoposide, doxorubicin, and cisplatin: a random assignment trial in gastric cancer.
- Sequential high-dose methotrexate and fluorouracil combined with doxorubicin--a step ahead in the treatment of advanced gastric cancer: a trial of the European Organization for Research and Treatment of Cancer Gastrointestinal Tract Cooperative Group.
- Controlled evaluation of three drug combination regimens versus fluorouracil alone for the therapy of advanced gastric cancer. North Central Cancer Treatment Group.
- Efficacy of the association of folinic acid and 5-fluorouracil alone versus folinic acid and 5-fluorouracil plus 4-epidoxorubicin in the treatment of advanced gastric carcinoma.
- Long-term survival after epirubicin, cisplatin and fluorouracil for gastric cancer: results of a randomized trial
- Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
- Randomised comparison of fluorouracil, epidoxorubicin and methotrexate (FEMTX) plus supportive care with supportive care alone in patients with non-resectable gastric cancer.
- Randomised phase II evaluation of irinotecan plus high-dose 5-fluorouracil and leucovorin (ILF) vs 5-fluorouracil, leucovorin, and etoposide (ELF) in untreated metastatic gastric cancer
- Phase II multi-institutional randomized trial of docetaxel plus cisplatin with or without fluorouracil in patients with untreated, advanced gastric, or gastroesophageal adenocarcinoma.
- The combination of cisplatin, doxorubicin, and mitomycin (PAM) compared with the FAM regimen in treating advanced gastric carcinoma: A phase II randomized trial of the Italian oncology group for clinical research
- Randomized phase III study comparing the efficacy and safety of irinotecan plus S-1 with S-1 alone as first-line treatment for advanced gastric cancer (study GC0301/TOP-002)
- Randomized phase III trial of fluorouracil alone versus fluorouracil plus cisplatin versus uracil and tegafur plus mitomycin in patients with unresectable, advanced gastric cancer: The Japan Clinical Oncology Group Study (JCOG9205).
- 5-Fluorouracil vs. epirubicin vs. 5-fluorouracil plus epirubicin in advanced gastric carcinoma
Cited by
- The prognostic roles of ALDH1 isoenzymes in gastric cancer
- RLIP76 decreases apoptosis through Akt/mTOR signaling pathway in gastric cancer
- Docetaxel, Capecitabine and Concurrent Radiotherapy for Gastric Cancer Patients with Postoperative Locoregional Recurrence
- Impact of Informative Censoring on Statistics Used in the Validation of Surrogate Endpoints in Oncology
- C5b-9 Staining Correlates With Clinical and Tumor Stage in Gastric Adenocarcinoma
- Multimodal treatment of gastric cancer in the west: Where are we going?
- TSPAN8 promotes gastric cancer growth and metastasis via ERK MAPK pathway.
- Prognostic Value of Baseline Neutrophil-Lymphocyte and Platelet-Lymphocyte Ratios in Local and Advanced Gastric Cancer Patients.
- Statistical evaluation of surrogate endpoints with examples from cancer clinical trials
- Combination or single-agent chemotherapy as adjuvant treatment of gastric cancer: A systematic review and meta-analysis of published trials.
- Chemotherapy for advanced gastric cancer.
- Key New Studies in Gastric and Esophageal Cancer
- Current and Future Therapies for Advanced Gastric Cancer.
- Neutrophil count and the inflammation-based glasgow prognostic score predict survival in patients with advanced gastric cancer receiving first-line chemotherapy.
- DCF intraperitoneal and intravenous dual chemotherapy regimen for advanced gastric cancer: A feasibility study
- Biomarkers for gastric cancer: prognostic, predictive or targets of therapy?
- Cisplatin or Not in Advanced Gastric Cancer: A Systematic Review and Meta-Analysis
- Targeted therapy in gastric cancer
- Weight loss at the first month of palliative chemotherapy predicts survival outcomes in patients with advanced gastric cancer
- Advances in molecular biomarkers for gastric cancer: miRNAs as emerging novel cancer markers
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