A method for the quantitative modification and estimation of carboxylic acid groups in proteins.

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Summary

The kinetics of the reaction indicates that there are limits to the variation of carbodiimide and nucleophile when quantitative modification is desired, but that a wide variety of reagents can be used if quantitative reaction is not essential.

Type
article
Published
1967-05-25
Cited by
790
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0
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Keywords

Carboxylic acid, Chemistry, Estimation, Biochemistry, Chromatography

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