Sox9 is required for cartilage formation

Keywords

SOX9, Chondrocyte, Chondrogenesis, Biology, Mesenchyme

References

• Cartilage Molecular AspectsBrian K. Hall, Stuart A. Newman — 1991
• Mutations in SOX9, the gene responsible for Campomelic dysplasia and autosomal sex reversal.Cheni Kwok, P A Weller, Silvana Guioli — 1995
• Manipulating the mouse embryo: A laboratory manualBrigid Hogan, Frank Costantini, Elizabeth Lacy — 1986
• Parallel expression of Sox9 and Col2a1 in cells undergoing chondrogenesisQi Zhao, Heidi Eberspaecher, Véronique Lefebvre — 1997
• Detection of messenger RNA by in situ hybridization to tissue sections and whole mounts.David G. Wilkinson, M. Ángela Nieto — 1993
• Teratocarcinomas and embryonic stem cells : a practical approachElizabeth J. Robertson, Rosa Beddington — 1987
• Biology of cartilage cellsRobert Amos Stockwell — 1979
• Heritable diseases of the skeleton. Part II: Molecular insights into skeletal development‐matrix components and their homeostasisStefan Mundlos, B. R. Olsen — 1997
• Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related geneJamie W. Foster, M. Dominguez-Steglich, Silvana Guioli — 1994
• Specific hybridization probes for mouse type I, II, III and IX collagen mRNAs.Marjo Metsäranta, D. Toman, Benoît De Crombrugghe — 1991
• Toward a molecular understanding of skeletal development.Adrian Erlebacher, Ellen Filvaroff, Stephen E. Gitelman — 1995
• Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birdsSara Morais da Silva, Adam Hacker, Vincent R. Harley — 1996
• Analysis of aggrecan and tenascin gene expression in mouse skeletal tissues by northern and in situ hybridization using species specific cDNA probes.Virpi Glumoff, Mikko Savontaus, Janne Vehanen — 1994
• Chondrocyte-specific Enhancer Elements in the Col11a2Gene Resemble the Col2a1 Tissue-specific Enhancer*Laura C. Bridgewater, Véronique Lefebvre, Benoît De Crombrugghe — 1998
• SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse.Ling-Jim Ng, Susan C. Wheatley, George E.O. Muscat — 1997
• Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression.Peter S. Mountford, Branko Zevnik, Annette Düwel — 1994
• The Sry-related gene Sox9 is expressed during chondrogenesis in mouse embryosEdwina M. Wright, Murray Hargrave, Jeffrey H. Christiansen — 1995
• SOX9 directly regulates the type-ll collagen geneDonald M. Bell, Keith K. H. Leung, Susan C. Wheatley — 1997
• Camptomelic dwarfism. A genetically determined mesenchymal disorder combined with sex reversal.M. Hovmöller, A. España Osuna, O. Eklöf — 2009
• Heritable diseases of the skeleton. Part I: Molecular insights into skeletal development‐transcription factors and signaling pathways 1Stefan Mundlos, B. R. Olsen — 1997

Cited by

• The Molecular Genetics of Bone FormationPierre J. Marie — 2001
• Skeletal development--Wnts are in control.Christine Hartmann — 2007
• Requisite roles of Runx2 and Cbfb in skeletal developmentSittipan Yotyodying — 2003
• Secondary chondrocyte-derived Ihh stimulates proliferation of periosteal cells during chick developmentSônia Maria Soares, Ivone Maria Martins Salomon, Dinamara Barreto dos Santos — 2003
• Differentiation of Mesenchymal Stem Cells Towards a Nucleus Pulposus-like Phenotype In Vitro: Implications for Cell-Based Transplantation TherapyDianne Frisko — 2004
• Highly conserved proximal promoter element harbouring paired Sox9-binding sites contributes to the tissue- and developmental stage-specific activity of the matrilin-1 gene.Francisco Santos Arrabal — 2005
• A predominantly articular cartilage-associated gene, SCRG1, is induced by glucocorticoid and stimulates chondrogenesis in vitro.Franz Hebel — 2006
• Human immortalized chondrocytes carrying heterozygous FGFR3 mutations: An in vitro model to study chondrodysplasiasA.E. Ignatenko, A.I. Mukhin, E.B. Ozerov — 2007
• Chordoma and chondrosarcoma gene profile: implications for immunotherapyLucia Boccacin — 2008
• Bone morphogenetic proteins are involved in the pathobiology of synovial chondromatosis.David Altimir — 2009
• Expression of master regulatory genes controlling skeletal development in benign cartilage and bone forming tumorsIstituto per lo sviluppo della formazione professionale dei lavoratori — 2010
• Gluococorticoid could influence extracellular matrix synthesis through Sox9 via p38 MAPK pathwayPaola Forero, César Ferrari — 2012
• The effect of ultrasound stimulation on the gene and protein expression of chondrocytes seeded in chitosan scaffoldsAna Ruas Alves — 2011
• The protein kinase MLTK regulates chondrogenesis by inducing the transcription factor Sox6Toshiyasu Suzuki, Morioh Kusakabe, Kei Nakayama — 2012
• Cartilage defects in Sox9 heterozygotesLillian Shum — 2001
• Contribution of the Interleukin‐6/STAT‐3 Signaling Pathway to Chondrogenic Differentiation of Human Mesenchymal Stem CellsMasahiro Kondo, Kunihiro Yamaoka, Kei Sakata — 2015
• A pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturationÁngel Fernández Ortega — 2015
• Signaling Pathways Regulating Cartilage Growth Plate Formation and ActivityGerald E. Edwards, J. F. Holloway — 2016
• BMP-2-enhanced chondrogenesis involves p38 MAPK-mediated down-regulation of Wnt-7a pathway.Eun‐Jung Jin, Sun-Young Lee, Young‐Ae Choi — 2006
• Overview of skeletal development.Tatsuya Kobayashi, Henry M. Kronenberg — 2014

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