Scavenger Receptors SR-AI/II and MARCO Limit Pulmonary Dendritic Cell Migration and Allergic Airway Inflammation1
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Summary
A novel role for SR-As expressed on lung DCs is identified in the down-regulation of specific immune responses to aeroallergens by the reduction of DC migration from the site of Ag uptake to the draining lymph nodes.
- Type
- article
- Published
- 2007-05-01
- Cited by
- 66
- References
- 46
- Access
- Open access
- OpenAlex
- https://openalex.org/W1564545512
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:19059951
Keywords
Scavenger receptor, Immunology, Lung, Lymph, Sensitization
References
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- Preprocessing of oligonucleotide array data
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- Role of the Scavenger Receptor MARCO in Alveolar Macrophage Binding of Unopsonized Environmental Particles
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- High Endothelial Cells of Postcapillary Venules Express the Scavenger Receptor in Human Peripheral Lymph Nodes
- Scavenger receptor-specific allergen delivery elicits IFN-gamma-dominated immunity and directs established TH2-dominated responses to a nonallergic phenotype.
Cited by
- Examination of MARCO Activity on Dendritic Cell Phenotype and Function Using a Gene Knockout Mouse
- Airway responses towards allergens – from the airway epithelium to T cells
- Intranasal CpG Therapy Attenuated Experimental Fungal Asthma in a TLR9-Dependent and -Independent Manner
- Oleic acid nanoemulsion for nasal vaccination: Impact on adjuvanticity based immune response
- Receptor-Dependent Phagocytosis of Clostridium sordellii by Human Decidual Macrophages
- Innate receptors and cellular defense against pulmonary infections
- Dendritic Cell Subsets are Key Regulators in the Immune System
- IFN-γ Attenuates Antigen-Induced Overall Immune Response in the Airway As a Th1-Type Immune Regulatory Cytokine1
- Involvement of soluble scavenger receptor A in suppression of T cell activation in patients with chronic hepatitis B
- Innate Immunity Immunomodulators in Post-Influenza Bacterial Pneumonia
- Autophagy Regulates Phagocytosis by Modulating the Expression of Scavenger Receptors
- Role of airway epithelial cells in development of asthma and allergic rhinitis.
- SR-A/MARCO-mediated ligand delivery enhances intracellular TLR and NLR function, but ligand scavenging from cell surface limits TLR4 response to pathogens.
- Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis
- Pattern Recognition Scavenger Receptor A/CD204 Regulates Airway Inflammatory Homeostasis Following Organic Dust Extract Exposures
- Interrelationship between Dendritic Cell Trafficking and Francisella tularensis Dissemination following Airway Infection
- Targeting MARCO can lead to enhanced dendritic cell motility and anti-melanoma activity
- Scavenger Receptor-A (CD204): A Two-Edged Sword in Health and Disease
- Dendritic cells in asthma and COPD: opportunities for drug development.
- Is the scavenger receptor MARCO a new immune checkpoint?
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