Three-dimensional segregation of supramolecular activation clusters in T cells

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Summary

The three-dimensional distribution of receptors and intracellular proteins that cluster at the contacts between T cells and APCs during antigen-specific interactions, Surprisingly, instead of showing uniform oligomerization, these proteins clustered into segregated three- dimensional domains within the cell contacts.

Type
article
Published
1998-09-03
Cited by
2,588
References
41

Keywords

Cell biology, Antigen, Chemistry, Receptor, Antigen-presenting cell

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