Towards an understanding of protein kinase B (PKB/Akt) function in mouse development

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Summary

It is found that PKBα/Akt1 was the predominant isoform in placenta and PKBγ/AKT3 is an important modulator of postnatal brain growth, and the two proteins have different roles in the maintenance of animal survival.

Type
dissertation
Published
2004-01-01
Cited by
0
References
126
Access
Open access

Keywords

AKT1, Protein kinase B, AKT2, PI3K/AKT/mTOR pathway, Proto-Oncogene Proteins c-akt

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