Exact and approximation algorithms for DNA sequence reconstruction

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Summary

This is the first treatment of Sequence Reconstruction with inexact data and unknown complementarity, and shows that maximizing the overlap minimizes the length, and that approximating (2) within a factor of α approximates Sequence Reconstruction within a factors of (1-ε)α under the overlap measure.

Type
article
Published
1992-01-01
Cited by
73
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0

Keywords

Substring, Sequence (biology), Combinatorics, Complement (music), Algorithm

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