Blood flow, metabolism, cellular microenvironment, and growth rate of human tumor xenografts.
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Summary
High metabolic rates concomitant with high flow values coincided with rapid tumor growth, and in order to design the best individualized therapy, flow-related data should supplement histological classification and clinical staging and grading.
- Type
- article
- Published
- 1989-07-15
- Cited by
- 294
- References
- 48
- OpenAlex
- https://openalex.org/W1539648696
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:8292699
Keywords
Pathology, Tumor microenvironment, Angiogenesis, Positron emission tomography, Medicine
References
- Cell line and growth site as relevant parameters governing tumor tissue oxygenation.
- Tumor Blood Circulation: Angiogenesis, Vascular Morphology and Blood Flow of Experimental and Human Tumors
- Population kinetics of carcinoma cells, capillary endothelial cells, and fibroblasts in a transplanted mouse mammary tumor.
- Glucose uptake, lactate release, ketone body turnover, metabolic micromilieu, and pH distributions in human breast cancer xenografts in nude rats.
- Quantitative determination of tumor blood flow and perfusion via deuterium nuclear magnetic resonance spectroscopy in mice.
- Heterogeneous oxygen partial pressure and pH distribution in C3H mouse mammary adenocarcinoma.
- The analysis of malignancy by cell fusion: the position in 1988.
- Determinants of tumor blood flow: a review.
- Transformation by the src oncogene alters glucose transport into rat and chicken cells by different mechanisms
- Tumor angiogenesis: a quantitative method for histologic grading.
- Angiogenesis induced by "normal" human breast tissue: a probable marker for precancer.
- The genetic origins of human cancer
- Angiogenesis as a marker of preneoplastic lesions of the human breast
- Hypoxia in neoplastic tissue.
- Angiogenic Activity as a Marker of Neoplastic and Preneoplastic Lesions of the Human Bladder
- Cell and environment interactions in tumor microregions: the multicell spheroid model.
- pH distributions in spontaneous and isotransplanted rat tumours.
- Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy.
- The ras oncogenes increase the intrinsic resistance of NIH 3T3 cells to ionizing radiation.
- Transient hypoxia enhances the frequency of dihydrofolate reductase gene amplification in Chinese hamster ovary cells.
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- Computerized histographic oxygen tension measurements of murine tumors.
- Clinical applications of intracranial perfusion MR imaging.
- Radiosensitization with normobaric oxygen and carbogen.
- Potentially lethal damage repair by total and quiescent tumor cells following various DNA-damaging treatments.
- The role of total parenteral nutrition in the patient with cancer.
- Oxygen tension in mouse mammary carcinomas and osteosarcomas after irradiation with reactor fission neutrons.
- Differentiation of malignant and benign musculoskeletal tumors: combined color and power Doppler US and spectral wave analysis.
- Measurements of tumor blood flow using intraperitoneal deuterium and 2H-NMR spectroscopy.
- Perfusion Magnetic Resonance Imaging to Assess Brain Tumor Responses to New Therapies.
- Expression and prognostic value of glucose transporters and hexokinases in tonsil and mobile tongue squamous cell carcinoma.
- Acidic stress induces apoptosis and inhibits angiogenesis in human bone marrow-derived endothelial progenitor cells
- Correlation of high lactate levels in head and neck tumors with incidence of metastasis.
- Interstitial fluid pressure, perfusion rate and oxygen tension in human melanoma xenografts.
- The hypoxic tumour microenvironment and metastatic progression
- Injectable formulations forming an implant in situ as vehicle of silica microparticles embedding superparamagnetic iron oxide nanoparticles for the local, magnetically mediated hyperthermia treatment of solid tumors
- In Vivo Assessment of Angioarchitecture and Microcirculation in Experimental Liver Cancer: A New Model in Rats
- Experimental cytokine therapy in renal cell carcinoma
- Anakoinosis: Communicative Reprogramming of Tumor Systems - for Rescuing from Chemorefractory Neoplasia
- NIR reflection spectroscopy based oxygen measurements and therapy monitoring in brain tissue and intracranial neoplasms. Correlation to MRI and angiography.
- Blood supply in melanoma xenografts is governed by the morphology of the supplying arteries.
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