The role of superoxide in the destruction of erythrocyte targets by human neutrophils.

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Summary

It is proposed that neutrophil-derived O2.- oxidizes oxyhemoglobin to generate methemoglobin and H2O2 which interact to form a cytotoxic complex capable of hemolyzing the erythrocyte target.

Type
article
Published
1980-10-25
Cited by
130
References
0
Access
Open access

Keywords

Superoxide, Neutrophile, Chemistry, Microbiology, Granulocyte

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