Vaccine-Induced, Simian Immunodeficiency Virus-Specific CD8+ T Cells Reduce Virus Replication but Do Not Protect from Simian Immunodeficiency Virus Disease Progression1

Keywords

Simian immunodeficiency virus, Viremia, Virology, Modified vaccinia Ankara, Immunology

References

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Cited by

• Viral CTL Escape Mutants Are Generated in Lymph Nodes and Subsequently Become Fixed in Plasma and Rectal Mucosa during Acute SIV Infection of MacaquesGustau Muñoz — 2011
• Dynamics of Simian Immunodeficiency Virus SIVmac239 Infection in Pigtail MacaquesNichole R. Klatt, Lauren Canary, Thomas H. Vanderford — 2011
• Safety and Reactogenicity of Canarypox ALVAC-HIV (vCP1521) and HIV-1 gp120 AIDSVAX B/E Vaccination in an Efficacy Trial in ThailandPunnee Pitisuttithum, Supachai Rerks‐Ngarm, Valai Bussaratid — 2011
• Expanding the Repertoire of Modified Vaccinia Ankara-Based Vaccine Vectors via Genetic Complementation StrategiesDavid A. Garber, Leigh A. O’Mara, Jun Zhao — 2009
• A Phase I Double Blind, Placebo-Controlled, Randomized Study of a Multigenic HIV-1 Adenovirus Subtype 35 Vector Vaccine in Healthy Uninfected AdultsMichael C. Keefer, Jill Gilmour, Peter Hayes — 2012
• Measuring human T cell responses in blood and gut samples using qualified methods suitable for evaluation of HIV vaccine candidates in clinical trials.Harry Kaltsidis, Hannah M. Cheeseman, Jakub Kopycinski — 2011
• Elevated Levels of Innate Immune Modulators in Lymph Nodes and Blood Are Associated with More-Rapid Disease Progression in Simian Immunodeficiency Virus-Infected MonkeysAndre Durudas, Jeffrey M. Milush, Hui‐Ling Chen — 2009
• Characterization of T-Bet and Eomes in Peripheral Human Immune CellsJames J. Knox, Gabriela L. Cosma, Michael R. Betts — 2014
• The immune response during acute HIV-1 infection: clues for vaccine developmentAndrew J. McMichael, Persephone Borrow, Georgia D. Tomaras — 2009
• Treatment of SIV-infected sooty mangabeys with a type-I IFN agonist results in decreased virus replication without inducing hyperimmune activation.Thomas H. Vanderford, Chloe K. Slichter, Kenneth A. Rogers — 2012
• Single-cell gene-expression profiling reveals qualitatively distinct CD8 T cells elicited by different gene-based vaccinesLukas Flatz, Rahul Roychoudhuri, Mitsuo Honda — 2011
• Immunodeficiency lentiviral infections in natural and non-natural hosts.Jason M. Brenchley, Mirko Paiardini — 2011
• TLR agonists and/or IL-15 adjuvanted mucosal SIV-vaccine reduced gut CD4+ memory T cell loss in SIVmac251-challenged rhesus macaquesYongjun Sui, Susan J. Gagnon, Amiran Dzutsev — 2011
• Inclusion of a CRF01_AE HIV envelope protein boost with a DNA/MVA prime-boost vaccine; impact on humoral and cellular immunogenicity and viral load reduction after SHIV-E challengeJosephine H. Cox, Maria G. Ferrari, Patricia L. Earl — 2012
• Attenuated poxvirus vectors MVA and NYVAC as promising vaccine cadidates against HIV/AIDSMariano Estéban — 2009
• Vaccine-induced T cells provide partial protection against high-dose rectal SIVmac239 challenge of rhesus macaques.Marcio O. Lasaro, Larissa H. Haut, Xiangyang Zhou — 2011
• Induction of balance and breadth in the immune response is beneficial for the control of SIVmac239 replication in rhesus monkeys.Caijun Sun, Lei Zhang, Maochao Zhang — 2010
• Activated CD4+CCR5+ T cells in the rectum predict increased SIV acquisition in SIVGag/Tat-vaccinated rhesus macaquesDiane G. Carnathan, Katherine S. Wetzel, Joana Yu — 2014
• Immunological and Virological Analyses of Rhesus Macaques Immunized with Chimpanzee Adenoviruses Expressing the Simian Immunodeficiency Virus Gag/Tat Fusion Protein and Challenged Intrarectally with Repeated Low Doses of SIVmacBarbara Cervasi, Diane G. Carnathan, Katherine M. Sheehan — 2013
• CD4saurus Rex &HIVelociraptor vs. development of clinically useful immunological markers: a Jurassic tale of frozen evolutionAndrea De Maria, Andrea Cossarizza — 2011

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