The superfamily of heptahelical receptors
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Summary
A personal perspective on events leading up to and flowing from the discovery of the close structural relationship between rhodopsin and the β2-adrenergic receptor is provided.
- Type
- article
- Published
- 2000-07-01
- Cited by
- 241
- References
- 61
- OpenAlex
- https://openalex.org/W1519384361
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:20491760
Keywords
G protein-coupled receptor, SUPERFAMILY, Receptor, Biology, Surprise
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- G Protein-coupled Receptors
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- Analysis of GPCR dimerization using acceptor photobleaching resonance energy transfer techniques.
- G protein-coupled receptor drug discovery: implications from the crystal structure of rhodopsin.
- Frizzleds: new members of the superfamily of G-protein-coupled receptors.
- “Saccharomyces cerevisiae G protein Coupled Receptor, Ste2p Interactions with its Ligand, α-factor and Cognate Gα protein, Gpa1p
- Possible role of intramembrane receptor-receptor interactions in memory and learning via formation of long-lived heteromeric complexes: focus on motor learning in the basal ganglia.
- ARF Family GTPases
- Transmembrane Signaling Protocols
- An investigation into the pharmacology and regulation of the M1, M3 and M4 muscarinic acetylcholine receptors
- Intramolecular Diels–Alder/Tsuji Allylation assembly of the functionalized trans-Decalin of Salvinorin A and sea lamprey migratory pheromone structure activity relationship studies.
- Thermal Fluctuations Of A GPCR: A Two Force Constant Model
- Protein prenylation inhibitors reveal a novel role for RhoA and RhoC in trafficking of G protein-coupled receptors through recycling endosomes
- Cross-Desensitization among CXCR1, CXCR2, and CCR5: Role of Protein Kinase C-ε1
- Novel Gbeta Mimic Kelch Proteins (Gpb1 and Gpb2 Connect G-Protein Signaling to Ras via Yeast Neurofibromin Homologs Ira1 and Ira2: A Model for Human NF1
- Stably transformed insect cell lines: tools for expression of secreted and membrane-anchored proteins and high-throughput screening platforms for drug and insecticide discovery.
- Characterisation of G protein-coupled receptor 56-signalling and its potential role in tumour progression
- Caractérisation d’un nouveau récepteur à octopamine exprimé chez la palourde Spisula solidissima
- Activation and Regulation of Platelet-Activating Factor Receptor: Role of Gi and Gq in Receptor-Mediated Chemotactic, Cytotoxic, and Cross-Regulatory Signals1
- Selective targeting of G‐protein‐coupled receptor subtypes with venom peptides
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