Activity-dependent scaling of quantal amplitude in neocortical neurons
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Summary
A new form of synaptic plasticity is described that increases or decreases the strength of all of a neuron's synaptic inputs as a function of activity, and may help to ensure that firing rates do not become saturated during developmental changes in the number and strength of synaptic inputs.
- Type
- article
- Published
- 1998-02-26
- Cited by
- 2,339
- References
- 29
- OpenAlex
- https://openalex.org/W1514853588
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4328177
Keywords
Excitatory postsynaptic potential, Synaptic augmentation, Neuroscience, Synaptic fatigue, Long-term potentiation
References
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- Activation of postsynaptically silent synapses during pairing-induced LTP in CA1 region of hippocampal slice
- Regulatory phosphorylation of AMPA-type glutamate receptors by CaM-KII during long-term potentiation.
- Synaptic economics: competition and cooperation in synaptic plasticity.
- Alterations in Synaptic Strength Preceding Axon Withdrawal
- Mechanisms underlying long-term potentiation of synaptic transmission.
- Pressure—volume relationships in the chest before and after death
Cited by
- Effective Neuronal Learning with Ineffective Hebbian Learning Rules
- Inactivity produces increases in neurotransmitter release and synapse size.
- Functional improvement of dystrophic muscle by myostatin blockade
- Cellular bases of behavioral plasticity: establishing and modifying synaptic circuits in the Drosophila genetic system.
- Phenomenological models of synaptic plasticity based on spike timing
- Role of pp2a/bβ2 and pka/akap1 in brain development and function via dynamin-related protein 1 (drp1) control of mitochondria shape and bioenergetics
- Synaptic plasticity in sleep: learning, homeostasis, and disease
- Inactivity-induced phrenic and hypoglossal motor facilitation are differentially expressed following intermittent vs. sustained neural apnea.
- Synaptopodin regulates denervation-induced homeostatic synaptic plasticity
- Neuroimmune regulation of homeostatic synaptic plasticity.
- A Literature Review of Bayes’ Theorem and Bayesian Belief Networks (BBN)
- N-methyl-D-aspartate receptors mediate activity-dependent down-regulation of potassium channel genes during the expression of homeostatic intrinsic plasticity
- Computational Maps in the Visual Cortex
- NEURONAL FIRING RATE HOMEOSTASIS IS INHIBITED BY SLEEP AND PROMOTED BY WAKE
- The Impact of Structural Heterogeneity on Excitation-Inhibition Balance in Cortical Networks
- Multiple shared mechanisms for homeostatic plasticity in rodent somatosensory and visual cortex
- Hebbian Learning in a Random Network Captures Selectivity Properties of the Prefrontal Cortex
- Estudi en mostres humanes i en cultius neuronals d’indicadors del sistema glutamatèrgic i dopaminèrgic en relació a l’exposició prolongada a contaminants orgànics tòxics persistents
- Neural Circuits on a Chip
- Sleep and Synaptic Plasticity in the Developing and Adult Brain
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