Activity-dependent scaling of quantal amplitude in neocortical neurons

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Summary

A new form of synaptic plasticity is described that increases or decreases the strength of all of a neuron's synaptic inputs as a function of activity, and may help to ensure that firing rates do not become saturated during developmental changes in the number and strength of synaptic inputs.

Type
article
Published
1998-02-26
Cited by
2,339
References
29

Keywords

Excitatory postsynaptic potential, Synaptic augmentation, Neuroscience, Synaptic fatigue, Long-term potentiation

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