Adipokines and their Involvement as a Target of New Drugs
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Summary
Adiponectin may be the most prominent example for the potential use of an adipokine in the treatment of obesity and obesity-associated metabolic diseases because of its anti-inflammatory and insulin sensitizing activity.
- Type
- article
- Published
- 2015-06-14
- Cited by
- 16
- References
- 156
- Access
- Open access
- OpenAlex
- https://openalex.org/W1511597337
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:55224210
Keywords
Medicine, Adipokine, Computational biology, Pharmacology, Omics
References
- Abstract 5551: Apelin is Necessary for the Maintenance of Insulin Sensitivity
- The adipocyte as an endocrine cell.
- Chemerin and apelin are positively correlated with inflammation in obese type 2 diabetic patients.
- Adipokines in obesity.
- Central nervous control of energy and glucose balance: focus on the central melanocortin system
- Update on obesity pharmacotherapy
- The hormone resistin links obesity to diabetes
- Restoration of leptin responsiveness in diet‐induced obese mice using an optimized leptin analog in combination with exendin‐4 or FGF21
- Mechanisms linking obesity with cardiovascular disease
- Metreleptin: First Global Approval
- Adipokines: A treasure trove for the discovery of biomarkers for metabolic disorders
- The biology of white adipocyte proliferation
- Vaspin prevents TNF-α-induced intracellular adhesion molecule-1 via inhibiting reactive oxygen species-dependent NF-κB and PKCθ activation in cultured rat vascular smooth muscle cells.
- Role of adiponectin system in insulin resistance.
- The genomic organization of mouse resistin reveals major differences from the human resistin: functional implications.
- Adipokines – removing road blocks to obesity and diabetes therapy
- Functional annotation of the human fat cell secretome
- New adipokines vaspin and omentin. Circulating levels and gene expression in adipose tissue from morbidly obese women
- Anti-obesity therapies
- Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes.
Cited by
- Appetite Regulatory Hormones – A Novel Target for Prevention, Management, and Treatment of Obesity
- Curcumin: A Naturally Occurring Modulator of Adipokines in Diabetes
- Saponins as adipokines modulator: A possible therapeutic intervention for type 2 diabetes
- THE ROLE OF LYSOPHOSPHATIDIC ACID AND AUTOTAXIN IN OBESITY-INDUCED CARDIAC INSULIN RESISTANCE
- Charakterystyka zmian metabolicznych zachodzących w procesie starzenia się tkanki tłuszczowej
- Discovery of potential visfatin activators using in silico docking and ADME predictions as therapy for type 2 diabetes
- Genetic variants of resistin and its plasma levels: Association with obesity and dyslipidemia related to type 2 diabetes susceptibility.
- Papel del polimorfismo del gen de la resistina (rs7139228) en la respuesta metabólica tras una dieta mediterránea hipocalórica
- Comprehensive Computational Studies of Naturally Occurring Kuguacins as Antidiabetic Agents by Targeting Visfatin
- Role of resistin (rs7139228) gene polymorphism with metabolic response after a hypocaloric mediterranean diet.
- Effects of Angiotensin Receptor Blockers on Apelin and Visfatin in Hypertension
- Adiponectin and gastric fundus: A potential target for gut–brain axis dysfunctions
- Endothelial function and peak heart rate in normal-weight women with polycystic ovary syndrome and normal-weight controls
- Associations of Serum and Saliva Resistin Levels with RETN Gene Polymorphism –420 C/G (rs1862513) among Iraqis’ Type II Diabetes
- Organic Molecular Strategy to Prevent Diabetes: An In Silico Screening of Berberine and Biguanides as Visfatin Antagonists
- Cytokines: Role in Homeostasis and Disease States
- The Medical Journal of Tikrit
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