Error detection for genetic data, using likelihood methods.
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Summary
A general method for detecting errors in pedigree genotyping data that is a variant of the likelihood-ratio test statistic that pinpoints individuals and loci with relatively unlikely genotypes is reviewed.
- Type
- article
- Published
- 1996-01-01
- Cited by
- 66
- References
- 20
- Access
- Open access
- OpenAlex
- https://openalex.org/W1511546866
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:10539486
Keywords
Pedigree chart, Statistics, Type I and type II errors, Statistic, Genotyping
References
- Evaluating pedigree data. I. The estimation of pedigree error in the presence of marker mistyping.
- Molecular and statistical approaches to the detection and correction of errors in genotype databases.
- Faster sequential genetic linkage computations.
- Influence of aberrant observations on high-resolution linkage analysis outcomes.
- Easy calculations of lod scores and genetic risks on small computers.
- Detecting marker inconsistencies in human gene mapping.
- Report of the Second International Workshop on Human Chromosome 6.
- Analysis of Human Genetic Linkage
- Construction of multilocus genetic linkage maps in humans.
- Strategies for multilocus linkage analysis in humans.
- Report of the committee on linkage and gene order.
- Kendall's advanced theory of statistics
- Computer-simulation methods in human linkage analysis.
- Standard maps of chromosome 10
- ERROR DETECTION IN GENETIC LINKAGE DATA FOR HUMAN PEDIGREES USING LIKELIHOOD RATIO METHODS
- Systematic detection of errors in genetic linkage data.
- The CEPH consortium linkage map of human chromosome 1.
- Influence of aberrant observations on high-resolution linkage analysis outcomes.
Cited by
- Factors affecting statistical power in the detection of genetic association.
- Improving Estimates of Genetic Maps: A Maximum Likelihood Approach
- Fine mapping of the nail-patella syndrome locus at 9q34.
- Major strengths and weaknesses of the lod score method.
- On the value of Mendelian laws of segregation in families: data quality control, imputation and beyond
- Identifying marker typing incompatibilities in linkage analysis.
- Implications of evolutionary history and population structure for the analysis of quantitative trait loci in the ancient conifer Araucaria cunninghamii
- Characterization of polycystic kidney disease in the Lewis Polycystic Kidney rat
- Power loss for multiallelic transmission/disequilibrium test when errors introduced: GAW11 simulated data
- Desarrollo de un mapa genético con marcadores AFLP y microsatélite en rodaballo ("Scophthalmus maximus L.")
- Genotyping error detection through tightly linked markers.
- Detecting low‐quality markers using map expanders
- The reliability of the Aspergillus nidulans physical map.
- Application of Homozygosity Haplotype Analysis to Genetic Mapping with High-Density SNP Genotype Data
- A Family-Based Likelihood Ratio Test for General Pedigree Structures That Allows for Genotyping Error and Missing Data
- Detection of genotyping errors and pseudo‐SNPs via deviations from Hardy‐Weinberg equilibrium
- Deviations from Hardy-Weinberg Equilibrium in Parental and Unaffected Sibling Genotype Data
- Associating phenotypes with molecular events: recent statistical advances and challenges underpinning microarray experiments
- Three-point appraisal of genetic linkage maps
- Power and Sample Size Calculations for Case-Control Genetic Association Tests when Errors Are Present: Application to Single Nucleotide Polymorphisms
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