Principles of early drug discovery

Keywords

Drug discovery, Identification (biology), Process (computing), Computer science, Risk analysis (engineering)

References

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Cited by

• New delivery systems for amphotericin B applied to the improvement of leishmaniasis treatment.Péter Halácsy, András Kornai, László Németh — 2015
• Review: Basics of Drug Development in RheumatologyGregor Knorr, Gerrit Lohmann — 2015
• Polypharmacology Shakes Hands with Complex Aetiopathology.Luca Pesenti — 2015
• Intracellular quantitative detection of human thymidylate synthase engagement with an unconventional inhibitor using tetracysteine-diarsenical-probe technologyGlauco Ponterini, Andrea Martello, Giorgia Pavesi — 2016
• Preclinical mouse model to monitor live Muc5b-producing conjunctival goblet cell density under pharmacological treatmentsJayadeva Uyangoda — 2017
• Protein degradation: a validated therapeutic strategy with exciting prospects.Olaya Fernández Herrero, Miguel Lorente — 2017
• The Molecular Design Research Network利幸 石井, 知美 加藤, 浩明 堀内 — 2018
• Where Do Recent Small Molecule Clinical Development Candidates Come From?Heinrich Schrand — 2018
• Making Sense of Pharmacology: Inverse Agonism and Functional SelectivityClaudia Méndez Endress, Irene Rostagno Eytel — 2018
• Potential Anti-Cancer Flavonoids Isolated From Caesalpinia bonduc Young Twigs and Leaves: Molecular Docking and In Silico StudiesKaren N. DSouza, Rod Whyte, Leanne Basham — 2019
• Computational drug repurposing in the age of COVID-19: mixing antiviral cocktails in silicoC.–P. Yuan — 2022
• Recent progress on structural bioinformatics research of cytochrome P450 and its impact on drug discovery.Tao Zhang, Dong‐Qing Wei — 2015
• Novel antiviral strategies for feline coronavirus and feline calicivirusPhillip McDonagh — 2014
• Structure-based drug discovery against a novel antimalarial drug target, S-adenosylmethionine decarboxylase/ornithine decarboxylaseJonathan James Reynolds — 2013
• Entwicklung von Teststrategien zur selektiven Hemmung von Enzymen der adrenalen Steroidsynthese unter besonderer Berücksichtigung von SpeziesunterschiedenSabrina Rau — 2014
• Every Silver Lining has a Cloud: The Scientific and Animal Welfare Issues Surrounding a New Approach to the Production of Transgenic AnimalsRobert D. Combes, Michael Balls — 2014
• Finding new scaffolds of JAK3 inhibitors in public database: 3D-QSAR models & shape-based screeningChangdev G. Gadhe, Eun-Hee Lee, Mi‐Hyun Kim — 2015
• Anti-diabetic effects of oleanolic acid and matrineXiao‐Yi Zeng — 2014
• Novel insight into drug repositioning: Methylthiouracil as a case in point.Moon‐Chang Baek, Byeongjin Jung, Hyejin Kang — 2015
• Design, synthesis and anticancer properties of novel oxa/azaspiro[4,5]trienones as potent apoptosis inducers through mitochondrial disruption.D. Yugandhar, Veena Nayak, Sivakumar Archana — 2015

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