Reactive oxygen species and oxidative DNA damage.
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Summary
A high rate of oxidative damage to mammalian DNA has been demonstrated by measuring oxidized DNA bases excreted in urine after DNA repair, directly related to the metabolic rate and inversely related to life span of the organism.
- Type
- article
- Published
- 1998-10-01
- Cited by
- 309
- References
- 106
- OpenAlex
- https://openalex.org/W1499932004
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24796072
Keywords
Peroxynitrite, DNA damage, Chemistry, Reactive oxygen species, Superoxide
References
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- Superoxide dismutases: an adaptation to a paramagnetic gas
- Effects of carbon dioxide/bicarbonate on induction of DNA single‐strand breaks and formation of 8‐nitroguanine, 8‐oxoguanine and base‐propenal mediated by peroxynitrite
- Oxidation of hydroquinone by copper: chemical mechanism and biological effects.
- Generation of reactive oxygen species during interaction of diesel exhaust particle components with NADPH-cytochrome P450 reductase and involvement of the bioactivation in the DNA damage.
Cited by
- Characterisation of inflammation in the central nervous system induced by lipoteichoic acid from Staphylococcus aureus : role of glia in the mechanisms of neuronal cell death
- Reduced antioxidant status for prolonged period due to repeated stress exposure in rat
- Effect of starvation stress on lipid peroxidation and lipid profile in rabbits.
- The role of nitric oxide in hindlimb remote ischaemic preconditioning of the liver
- In vitro determination of anti-oxidant activities of Garuga pinnata Roxb
- Role of alcoholic root concoctions on haematological and renohepatic function markers among HIV patients in some rural communities in Eastern Nigeria.
- Modulation of electrical stimulation applied to human physiology and clinical diagnostic
- DNA damage response and senescence in endothelial cells of human cerebral cortex and relation to Alzheimer's neuropathology progression: a population‐based study in the Medical Research Council Cognitive Function and Ageing Study (MRC‐CFAS) cohort
- Oxidative Stress Induced by Lipid Peroxidation Is Related with Inflammation of Demyelination and Neurodegeneration in Multiple Sclerosis
- Dietary vitamin E and physical exercise: II. Antioxidant status and lipofuscin-like substances in aging rat heart.
- Estudos de reparo de DNA por excisão de nucleotídeos em lesões oxidativas em células de mamíferos.
- Reactive oxygen species and energy machinery: an integrated dynamic model
- Evaluation of In-vitro Antioxidant Activity of Seagrasses: Signals for Potential Alternate Source
- The effect of Fe2O3 and ZnO nanoparticles on cytotoxicity and glucose metabolism in lung epithelial cells
- Antioxidant, Antinociceptive and Anti-inflammatory Activities of Ethanolic Extract of Leaves of Alocasia indica (Schott.)
- Reference gene selection for qPCR in Ammopiptanthus mongolicus under abiotic stresses and expression analysis of seven ROS-scavenging enzyme genes
- Effect of vitamin B6 on oxygen radicals, mitochondrial membrane potential, and lipid peroxidation in H2O2-treated U937 monocytes.
- Arsenic induces DNA damage via reactive oxygen species in human cells
- Free radical scavenging and anti-inflammatory properties of Lagerstroemia speciosa (L)
- Effect of palm oil on oxidative stress-induced hypertension in Sprague-Dawley rats.
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