Rapid, one-step fabrication and loading of nanoscale 1,2-distearoyl-sn-glycero-3-phosphocholine liposomes in a simple, double flow-focusing microfluidic device.
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Summary
A double flow-focusing microfluidic geometry capable of sub-hour synthesis and controlled loading of tunable liposomes is demonstrated: a microscope-slide-sized alternative to conventional manufacturing processes.
- Type
- article
- Published
- 2015-07-01
- Cited by
- 12
- References
- 31
- Access
- Open access
- OpenAlex
- https://openalex.org/W768813405
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:30445226
Keywords
Microfluidics, Liposome, Lipid bilayer, Materials science, Biocompatible material
References
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- Analysis of a laminar-flow diffusional mixer for directed self-assembly of liposomes.
- Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane).
- Microfluidic Remote Loading for Rapid Single-Step Liposomal Drug Preparation
- Liposomes: from a clinically established drug delivery system to a nanoparticle platform for theranostic nanomedicine.
- Liposome technology for cardiovascular disease treatment and diagnosis
- Liposomes in cosmeceutics
- Recent advances with liposomes as pharmaceutical carriers
- Microfluidic directed formation of liposomes of controlled size.
- Liposomal drug delivery systems: from concept to clinical applications.
- Continuous flow production of cationic liposomes at high lipid concentration in microfluidic devices for gene delivery applications
- Behavior of fluorescent cholesterol analogues dehydroergosterol and cholestatrienol in lipid bilayers: a molecular dynamics study.
- Liposome: classification, preparation, and applications
- Liposomes: technologies and analytical applications.
Cited by
- Microfluidic solutions enabling continuous processing and monitoring of biological samples: A review.
- Real-time measurement of complex refractive indices with surface plasmon resonance
- A step forward towards the design of a continuous process to produce hybrid liposome/protein microcapsules
- Liposomes : a multifaceted delivery system
- Continuous Production of the Nanoscale Liposome in a Double Flow-Focusing Microfluidic Device
- Double flow focusing microfluidic-assisted based preparation of methotrexate–loaded liposomal nanoparticles: Encapsulation efficacy, drug release and stability
- Lipid in Chips: A Brief Review of Liposomes Formation by Microfluidics
- Microfluidic synthesis of lipid-based nanoparticles for drug delivery: recent advances and opportunities.
- A Novel Acoustic Modulation of Oscillating Thin Elastic Membrane for Enhanced Streaming in Microfluidics and Nanoscale Liposome Production
- Advanced microfluidic strategies for core-shell nanoparticles: the next-generation of polymeric and lipid-based drug nanocarriers
- Quality by design (QbD) liposomes engineering using 3D printed Tesla microfluidic arrays
- Advances in microfluidic and artificial intelligence-assisted design of liposomes for drug delivery applications
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