An Investigation into the Use of a Plant-Expressed Virus-Like Particle as an Oral Vaccine Candidate
Explore this paper's citation graph
Summary
An original investigation into the possible applications of plant-expressed HBcAg VLPs for oral drug delivery suggested that the antigen was unstable when subjected to various simulated gastric fluids.
- Type
- dissertation
- Published
- 2013-08-01
- Cited by
- 0
- References
- 270
- Access
- Open access
- OpenAlex
- https://openalex.org/W752453140
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:82505326
Keywords
HBcAg, Antigen, Virus-like particle, Chemistry, Virology
References
- An infrared spectroscopic study of the interactions of carbohydrates with dried proteins.
- Hepatitis B core particles as a universal display model: a structure‐function basis for development
- Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria
- Diffusion of macromolecules and virus-like particles in human cervical mucus.
- Structural comparisons of hepatitis B core antigen particles with different C-terminal lengths.
- Rapid appearance of M cells after microbial challenge is restricted at the periphery of the follicle-associated epithelium of Peyer's patch.
- Particle Transcytosis Across the Human Intestinal Epithelium : Model Development and Target Identification for Improved Drug Delivery
- Collaboration of epithelial cells with organized mucosal lymphoid tissues
- Unsafe injections in the developing world and transmission of bloodborne pathogens: a review.
- The structure of hepadnaviral core antigens. Identification of free thiols and determination of the disulfide bonding pattern.
- Size-Dependent Immunogenicity: Therapeutic and Protective Properties of Nano-Vaccines against Tumors1
- In Vitro Permeability Across Caco-2 Cells (Colonic) Can Predict In Vivo (Small Intestinal) Absorption in Man—Fact or Myth
- Stability of the recombinant hepatitis B core antigen
- A protease-sensitive hinge linking the two domains of the hepatitis B virus core protein is exposed on the viral capsid surface
- Absorption of Polyethylene Glycols 600 Through 2000: The Molecular Weight Dependence of Gastrointestinal and Nasal Absorption
- Microencapsulation: A promising technique for controlled drug delivery
- Immune response to hepatitis B virus core antigen (HBcAg): localization of T cell recognition sites within HBcAg/HBeAg.
- Caco-2 Cell Monolayers as a Model for Drug Transport Across the Intestinal Mucosa
- Proline-138 is essential for the assembly of hepatitis B virus core protein.
- A plant‐derived edible vaccine against hepatitis B virus
Cited by
No citing papers recorded for this paper.
Related papers
- Modular virus-like particles for sublingual vaccination against group A streptococcus.
- Adjusted Particle Size Eliminates the Need of Linkage of Antigen and Adjuvants for Appropriated T Cell Responses in Virus-Like Particle-Based Vaccines
- Recombinant in vitro assembled hepatitis C virus core particles induce strong specific immunity enhanced by formulation with an oil-based adjuvant.
- Intranasal delivery of Norwalk virus-like particles formulated in an in-situ gelling, dry powder vaccine
- Cellular and humoral responses to microencapsulated Yersinia pestis subunit vaccines following oral delivery.
- The release and induced immune responses of a plant-made and delivered antigen in the mouse gut.
- Combinatorial Approach of Antigen Delivery Using M Cell-Homing Peptide and Mucoadhesive Vehicle to Enhance the Efficacy of Oral Vaccine.
- Polyethyleneimine-complexed charge-reversed yeast cell walls for the enhanced oral delivery of pseudovirus-based antigens.