Repetitive head trauma, chronic traumatic encephalopathy and tau: Challenges in translating from mice to men.
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Summary
The current literature and current opinion list of recommended features to consider for successfully modeling CTE in animals to better understand the pathobiology and develop therapeutics and diagnostics, and critical factors, which might influence outcome are provided.
- Type
- review
- Published
- 2016-01-01
- Cited by
- 99
- References
- 193
- OpenAlex
- https://openalex.org/W610565812
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:37054067
Keywords
Chronic traumatic encephalopathy, Traumatic brain injury, Medicine, Concussion, Terminology
References
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Cited by
- Functionally-Detected Cognitive Impairment in High School Football Players without Clinically-Diagnosed Concussion
- Mechanical stress models of Alzheimer's disease pathology
- Modeling Chronic Traumatic Encephalopathy: The Way Forward for Future Discovery
- Alterations of functional properties of hippocampal networks following repetitive closed-head injury.
- Chronic Exposure to Androgenic-Anabolic Steroids Exacerbates Axonal Injury and Microgliosis in the CHIMERA Mouse Model of Repetitive Concussion
- Differential detection of impact site versus rotational site injury by magnetic resonance imaging and microglial morphology in an unrestrained mild closed head injury model
- Mapping the Connectome Following Traumatic Brain Injury
- Review Article Mechanical stress models of Alzheimer's disease pathology
- HISTOLOGICAL AND BEHAVIORAL CONSEQUENCES OF REPEATED MILD TRAUMATIC BRAIN INJURY IN MICE
- Chronic Repetitive Mild Traumatic Brain Injury Results in Reduced Cerebral Blood Flow, Axonal Injury, Gliosis, and Increased T-Tau and Tau Oligomers
- Using mouse models to investigate the pathophysiology, treatment, and prevention of post‐traumatic osteoarthritis
- Changing paradigm in mild traumatic brain injury research
- Repeated Closed Head Injury in Mice Results in Sustained Motor and Memory Deficits and Chronic Cellular Changes
- Concussions and Repercussions
- Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage
- Elucidating and Pharmacologically Targeting Secondary Injury Cascades following Neural Injury
- Defective synthesis and release of astrocytic thrombospondin‐1 mediates the neuronal TDP‐43 proteinopathy, resulting in defects in neuronal integrity associated with chronic traumatic encephalopathy: in vitro studies
- Pumping the Brakes: Neurotrophic Factors for the Prevention of Cognitive Impairment and Dementia after Traumatic Brain Injury
- Chronic Traumatic Encephalopathy in Athletes Involved with High-impact Sports.
- Inflammatory changes in optic nerve after closed-head repeated traumatic brain injury: Preliminary study
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