Plant-based strategies aimed at expressing a functional human adenosine deaminase at high levels
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Summary
As a preliminary step to produce biologically active human ADA in transgenic tobacco plants and tobacco BY-2 cell suspensions a human ADA cDNA has been inserted into a plant expression vector under the control of the CaMV 35S promoter and terminator.
- Type
- dissertation
- Published
- 2012-10-01
- Cited by
- 0
- References
- 109
- Access
- Open access
- OpenAlex
- https://openalex.org/W600573195
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:82709668
Keywords
Adenosine deaminase, Recombinant DNA, Transgene, Biology, Biochemistry
References
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- Pathologic basis of disease
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- N-glycosylation potential of maize: The human lactoferrin used as a model
- Accumulation of a thermostable endo-1,4-β-D-glucanase in the apoplast of Arabidopsis thaliana leaves
- Expression of murine adenosine deaminase (ADA) in transgenic maize
- Accumulation of Recombinant SARS-CoV Spike Protein in Plant Cytosol and Chloroplasts Indicate Potential for Development of Plant-Derived Oral Vaccines
- Long-term chimerism and B-cell function after bone marrow transplantation in patients with severe combined immunodeficiency with B cells: A single-center study of 22 patients.
- Human α-mannosidase produced in transgenic tobacco plants is processed in human α-mannosidosis cell lines.
- Protein body-inducing fusions for high-level production and purification of recombinant proteins in plants.
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