The effects of inhibition of gluconeogenesis on ketogenesis in starved and diabetic rats.
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Summary
It was concluded that gluconeogenesis may stimulate ketogenesis by as much as 30% in severe diabetic ketoacidosis and an inhibition of hepatic fatty acid oxidation by the more reduced mitochondrial redox state was seen.
- Type
- article
- Published
- 1975-06-01
- Cited by
- 52
- References
- 1
- Access
- Open access
- OpenAlex
- https://openalex.org/W308073524
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:38724351
Keywords
Ketogenesis, Gluconeogenesis, Internal medicine, Endocrinology, Ketone bodies
References
Cited by
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- Mechanisms of regulation of the partition of fatty acids between oxidation and esterification in the liver.
- The indirect pathway of hepatic glycogen synthesis and reduction of food intake by metabolic inhibitors.
- The Role of Regulation of Tissue Pyruvate Dehydrogenase Complex Activity during the Starved‐to‐Fed Transition a
- Gluconeogenesis and ammoniagenesis in rat kidney: Effect of 3‐mercaptopicolinic acid
- Octanoate metabolism in primary culture of chicken hepatocytes: evidence for high-capacity octanoate esterification.
- The functions and regulation of tryptophan pyrrolase.
- Metabolomic assays of the concentration and mass isotopomer distribution of gluconeogenic and citric acid cycle intermediates
- Significance of acetoacetate/beta-hydroxybutyrate ratio in arterial blood as an indicator of the severity of hemorrhagic shock.
- Phosphoenolpyruvate carboxykinase and gluconeogenesis in cotyledons of Cucurbita pepo.
- The effect of bacterial infections on ketone concentrations in rat liver and blood and on free fatty acid concentrations in rat blood.
- Structural requirements for pyridine carboxylate effects on phosphoenolpyruvate carboxykinase
- Responses of hepatic phosphoenolypyruvate carboxykinase activities from normal and diabetic rats to quinolinate inhibition and ferrous ion activation.
- The Metabolic Impact of Gluconeogenic Blockade in Tumor‐Bearing Man
- Effect of quinolinic acid on the metabolite profile and regulation of carbohydrate and lipid metabolism in the liver of diabetic rats.
- CAL in the biochemical laboratory
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