p-Chloroaniline, t-butylhydroquinone, and methyl carbamate: Rat in vivo comet test, JaCVAM trial phase 4.2.
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Summary
P-Chloroaniline, t-butylhydroquinone, and methyl carbamate were examined for in vivo rat alkaline comet assay and all values obtained fell within the current vehicle historical control range and within the negative control range for mean % tail intensity set by the Validation Management Team.
- Type
- article
- Published
- 2015-07-01
- Cited by
- 10
- References
- 12
- OpenAlex
- https://openalex.org/W307586905
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:6407408
Keywords
In vivo, Carbamate, Stomach, Intensity (physics), Ethyl carbamate
References
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- Fourth International Workgroup on Genotoxicity testing: results of the in vivo Comet assay workgroup.
- A Multiple Comparison Procedure for Comparing Several Treatments with a Control
- JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results.
- Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing
- Recommendations for conducting the in vivo alkaline Comet assay. 4th International Comet Assay Workshop.
- A multiple comparison rank sum test: Treatments versus control.
- Individual Comparisons by Ranking Methods
- Properties of sufficiency and statistical tests
- Properties of Sufficiency and Statistical Tests
Cited by
- Re-analysis results using medians of the data from the JaCVAM-organized international validation study of the in vivo rat alkaline comet assay.
- Diverse cellular actions of tert-butylhydroquinone, a food additive, on rat thymocytes.
- Assessment of the mutagenic potential of para‐chloroaniline and aniline in the liver, spleen, and bone marrow of Big Blue® rats with micronuclei analysis in peripheral blood
- Validation of the 3D reconstructed human skin Comet assay, an animal-free alternative for following-up positive results from standard in vitro genotoxicity assays
- Methodological aspects of DNA-comet assay in vivo in pre-clinical research
- A weight of evidence assessment of the genotoxicity of 2,6-xylidine based on existing and new data, with relevance to safety of lidocaine exposure.
- Evaluation of the Liver and Blood Micronucleus, and Comet Assay Endpoints in a 14-Day Repeated Dose Study with Methyl Carbamate and 1, 3-Propane Sultone.
- Formation of hepatocyte cytoplasmic inclusions and their contribution to methylcarbamate-induced hepatocarcinogenesis in F344 rats.
- Efek Hepatoprotektor Air Kelapa (Cocos nucifera L) dan Asam Folat terhadap Gambaran Histopatologi Hati Tikus Wistar Betina Hamil (Rattus norvegicus) yang Diinduksi Karbamat
- SOME NITROBENZENES AND OTHER INDUSTRIAL CHEMICALS
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