Development of injectable pH-degradable polymeric particles containing thrombin for minimally invasive delivery of fibrin glue to the heart post-myocardial infraction
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Summary
The results gathered for the particles developed herein suggest that this the injection of thrombin-loaded polymeric particles is a viable option for the creation of a natural scaffold at the site of a myocardial infarct to promote cell survival and decrease the risk for heart failure in the future.
- Type
- article
- Published
- 2014-12-20
- Cited by
- 0
- References
- 245
- Access
- Open access
- OpenAlex
- https://openalex.org/W238017387
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:135833839
Keywords
Fibrin glue, Drug delivery, Thrombin, Biomedical engineering, Myocardial infarction
References
- The Stabilization and Encapsulation of Human Growth Hormone into Biodegradable Microspheres
- Improvement of Dissolution Rates of Poorly Water Soluble APIs Using Novel Spray Freezing into Liquid Technology
- The structures and proteolytic specificities of autolysed human thrombin.
- Thrombin: Structure, Biochemistry, Measurement, and Status in Clinical Medicine
- The Preparation and Evaluation of Drug-Containing Poly(dl-lactide) Microspheres Formed by the Solvent Evaporation Method
- Protein Spray-Freeze Drying. Effect of Atomization Conditions on Particle Size and Stability
- Embolization of a common carotid aneurysm with rhVEGF coupled to a pH-responsive chitosan in a rat model.
- Protein Inhalation Powders: Spray Drying vs Spray Freeze Drying
- Thrombin as procoagulant and anticoagulant.
- The Preparation and Characterization of Poly(lactide-co-glycolide) Microparticles. II. The Entrapment of a Model Protein Using a (Water-in-Oil)-in-Water Emulsion Solvent Evaporation Technique
- Mechanisms of solvent evaporation encapsulation processes: prediction of solvent evaporation rate.
- XX. On the equilibrium of liquid conducting masses charged with electricity
- Trimethylated chitosan-conjugated PLGA nanoparticles for the delivery of drugs to the brain.
- Concurrent Binding and Delivery of Proteins and Lipophilic Small Molecules Using Polymeric Nanogels
- Near-Infrared Light-Responsive Core-Shell Nanogels for Targeted Drug Delivery
- Spray-dried powders for pulmonary drug delivery.
- Investigation of processing parameters of spray freezing into liquid to prepare polyethylene glycol polymeric particles for drug delivery
- Fabrication of monodispersed Taxol-loaded particles using electrohydrodynamic atomization.
- Photoresponsive nanogels formed by the self-assembly of spiropyrane-bearing pullulan that act as artificial molecular chaperones.
- Preparation of Poly(D,L‐lactide) and Copoly(lactide‐glycolide) Microspheres of Uniform Size
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